SavedAdd your journal

Journals / Acta Veterinaria Eurasia / 2021 / Cilt: 47 - Sayı: 3

Histomorphological Examination of Skin Wound Healing Under the Effect of Avocado Oil in Wistar Rats

Mohammad Reza EBAD SICHANI
Mehdi FARID
Elham MOGHTADAEI KHORASGANI
Pages
1–8
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Hence, it can be an appropriate option for the treatment of skin wounds.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Given the presence of most fatty acids and proven anti-inflammatory properties in avocado oil, the present study tried to examine its effect on the skin wound healing process in rats.
📊
Key Findings & Data:A total of 30 rats with the same weight range were randomly divided into three groups, including control, treatment with avocado oil, and treatment with phenytoin after anesthesia, and a full-thickness skin wound with an area of 4 cm was created on their backs.
💡
Conclusion & Impact:Hence, it can be an appropriate option for the treatment of skin wounds.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Given the presence of most fatty acids and proven anti-inflammatory properties in avocado oil, the present study tried to examine its effect on the skin wound healing process in rats. A total of 30 rats with the same weight range were randomly divided into three groups, including control, treatment with avocado oil, and treatment with phenytoin after anesthesia, and a full-thickness skin wound with an area of 4 cm was created on their backs. Wound healing was examined histologically and the wound area was examined during the 3rd, 7th, and 14th days. Based on the results of the present study, a significant relationship was observed between the group treated with avocado oil and the group treated with phenytoin in terms of wound area in rats (p < .05). During the study, the wound area of the group treated with avocado oil was significantly smaller than that of the group treated with phenytoin and the control group. The research results revealed that avocado oil can increase collagen synthesis, reduce the number of inflammatory cells, accelerate the process of coagulation, and accelerate the regeneration of epithelium, thus accelerating the healing process. Hence, it can be an appropriate option for the treatment of skin wounds.

🔖

Cite This Article

SICHANI, M. R. E., FARID, M., KHORASGANI, E. M. (2021). Histomorphological Examination of Skin Wound Healing Under the Effect of Avocado Oil in Wistar Rats. Acta Veterinaria Eurasia, Cilt: 47 - Sayı: 3, 1–8. https://ajindex.com/articles/413766

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Balbino, C. A., Pereira, L. M., & Curi, R. (2005). Mechanisms involved in wound healing: A revision. Brazilian Journal of Pharmaceutical Sciences, 41, 27–51. [CrossRef] Bruce, A., & Schaffer, B. (2012). The avocado: Botany, production and uses (2nd ed, pp. 45–501).
  2. Wolstenholme, Boston, USA: Antony William Whiley. Camila, A., Eryvelton, F., Rafaella, B., & Daniele, C. (2013). Effect of semisolid formulation of Persea Americana Mill (Avocado) oil onwound healing in rats. Evidence-Based Complementary and Alternative Medicine, 2013, 1–8.
  3. Deodhar, A. K., & Rana, R. E. (1997). Surgical physiology of wound healing: A review. Journal of Postgraduate Medicine, 43(2), 52–56. [CrossRef]) Falzon, C. C., & Balabanova, A. (2017). Phytotherapy: An introduction to herbal medicine. Primary Care, 44(2), 217–227. [CrossRef] Flores, M. A., Perez-Camino, M. C., & Troca, J. (2014). Preliminary studies on composition, quality and oxidative stability of commercial avocado oil produced in Chile. Journal of Food Science and Engineering, 4, 21–26.
  4. Fulgoni, V. L., Dreher, M., & Davenport, A. J. (2013). Avocado consumption is associated with better diet quality and nutrient intake, and lower metabolic syndrome risk in US adult: Results from the national health and nutrition examination survey, 2001–2008. Nutrition Journal, 12, 1. [CrossRef] Ghasemi, A., & Ketabi, M. (2018). Antimicrobial activity of Avocado leaf extract in subject with poor oral hygiene: An invitro study. Journal Infohan Dental School, 14, 410–418.
  5. Groeber, F., Holeiter, M., & Hampel, M. (2011). Skin tissue engineering— in vivo and vitro applications. Advanced Drug Delivery Reviews, 128, 352–366.
  6. Hatz, R. A., Niedner, R., Vanscheidt, W., & Westerhof, W. (1994). Wound healing and wound management (4th ed, pp. 1–68).
  7. Berlin, Germany: Springer-Verlag. Jain, U., & Gupta, N. (2010). Prominent wound healing properties of indigenous medicines. Journal of Natural Pharmaceuticals, 1(1), 2–13. [CrossRef] Kawagishi, H., Fukumoto, Y., Hatakeyama, M., He, P., Arimoto, H., Matsuzawa, T., Arimoto, Y., Suganuma, H., Inakuma, T., & Sugiyama, K. (2001). Liver injury suppressing compounds from avocado (Persea americana). Journal of Agricultural and Food Chemistry, 49(5), 2215–2221. [CrossRef] Larijani, L., Ghasemi, M., Abedian Kenari, S., Naghshvar, F., Azadbakht, M., & Yazdani Cherati, J. (2012). Investigating the effects of 4 types of avocado fruit extract on squamous cell carcinoma of the mouth and esophagus in comparison with perip