Although plasmapheresis was started with concomitant intravenous immunoglobulin and steroid therapy, the patient died.
📌 3 Key Takeaways
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Objective & Hypothesis:A female with no previous history of bleeding presented with active bleeding from multiple body sites, declining hemoglolobin levels, and markedly prolonged prothrombin times (PT), and activated par-tial thromboplastin times (APTT) with incomplete correction on PT mix assays.
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Key Findings & Data:This patient showed a severe deficiency of factor X.
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Conclusion & Impact:Although plasmapheresis was started with concomitant intravenous immunoglobulin and steroid therapy, the patient died.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Steroidler · Kan pıhtılaşma bozuklukları · kalıtsal
Özet
A female with no previous history of bleeding presented with active bleeding from multiple body sites, declining hemoglolobin levels, and markedly prolonged prothrombin times (PT), and activated par-tial thromboplastin times (APTT) with incomplete correction on PT mix assays. This patient showed a severe deficiency of factor X. FX levels and bleeding were refractory to multiple transfusions of fresh fro-zen plasma. Although plasmapheresis was started with concomitant intravenous immunoglobulin and steroid therapy, the patient died.
AYLI, M., DAĞDAŞ, S., YILMAZ, S. (2000). Isolated acquired FX deficiency: A case report. Turkish Journal of Hematology, Cilt: 17 - Sayı: 1, 29–32. https://ajindex.com/articles/413451