SavedAdd your journal

Journals / Turkish Journal of Hematology / 2009 / Cilt: 26 - Sayı: 3

Irak’ın Erbil şehrindeki bir grup gebe kadında trombositopeni prevalansı ve etiyolojik sınıflandırması

Prevalence and etiological classification of thrombocytopenia among a group of pregnant women in Erbil city, Iraq

Rawand Pouls SHAMOON
Nawsherman Sadiq MUHAMMED
Muhammed Salih JAFF
Pages
123–128
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

No ‎maternal or neonatal bleeding complications were observed.‎

📌 3 Key Takeaways

🎯
Objective & Hypothesis:OBJECTIVE: To determine prevalence and define causes of pregnancy associated thrombocytopenia METHODS: A total of 850 pregnant women at different ages of gestation were screened for ‎thrombocytopenia.
📊
Key Findings & Data:A control group of 150 age-matched nonpregnant women were tested for ‎platelet count.
💡
Conclusion & Impact:No ‎maternal or neonatal bleeding complications were observed.‎
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Gebelik komplikasyonları · Trombosit sayısı · Preeklampsi

Abstract

OBJECTIVE: To determine prevalence and define causes of pregnancy associated thrombocytopenia METHODS: A total of 850 pregnant women at different ages of gestation were screened for ‎thrombocytopenia. A control group of 150 age-matched nonpregnant women were tested for ‎platelet count. Neoborns of thrombocytopenic women were tested within 24 hours of ‎delivery and reassessment of women's platelets was done within 7-10 days post delivery. ‎ RESULTS: The mean platelet count in pregnant women was significantly lower than in nonpregnant ‎women (221±59.9 vs. 273±66.9). Thrombocytopenia affected 8% of cases, with peak ‎incidence during the third trimester. Gestational thrombocytopenia was found to be the ‎principal cause (73.8%); hypertensive disorders caused thrombocytopenia in 23% of cases ‎and two cases (4%) were due to immune thrombocytopenic purpura. No maternal or fetal ‎complications were noted. The mean platelet count of 51 neoborns of thrombocytopenic ‎women was (240 ± 7.1). Two neoborns (4%) had low platelet counts.‎ CONCLUSION: Majority of thrombocytopenias were mild gestational and occurred in late in pregnancy. No ‎maternal or neonatal bleeding complications were observed.‎

Özet

AMAÇ: Gebelik ile ilişkili trombositopeni prevalansını saptamak ve nedenlerini tanımlamak. YÖNTEMLER: Farklı gebelik haftalarındaki 850 gebe kadın trombositopeni yönünden tarandı. Gebe olmayan ve yaşları eşleştirilmiş 150 kadından oluşan kontrol grubu, trombosit sayısı yönünden değerlendirildi. Trombositopenik kadınların yeni doğan bebekleri doğumun 24 saati içinde test edildi ve kadınların trombositleri doğumdan sonraki 7-10 gün içinde tekrar değerlendirildi. BULGULAR: Gebe kadınlarda ortalama trombosit sayısı gebe olmayan kadınlara göre anlamlı derecede düşük bulundu (221±59,9/mm3 ve 273±66.9/mm3). Trombositopeni, 3. trimesterde en yüksek insidans ile olguların %8’ini etkiledi. Gestasyonel trombositopeninin (%73,8) ana neden olduğu bulundu, trombositopeniye olguların %23’ünde hipertansif bozuklar ve 2 olguda (%4) ise immün trombositopenik purpura, neden oldu. Maternal veya fötal hiçbir komplikasyon belirlenmedi. Trombositopenik kadınlardan doğan 51 yeni doğanda ortalama trombosit sayısı 240±71 idi. İki (%4) yeni doğanda trombosit sayıları düşük bulundu. SONUÇ: Trombositopenilerin çoğunluğu hafif gestasyonel tarzda idi ve gebeliğin geç dönemlerinde ortaya çıkmıştı. Maternal veya neonatal hiçbir kanama komplikasyonu gözlenmedi.

🔖

Cite This Article

SHAMOON, R. P., MUHAMMED, N. S., JAFF, M. S. (2009). Irak’ın Erbil şehrindeki bir grup gebe kadında trombositopeni prevalansı ve etiyolojik sınıflandırması. Turkish Journal of Hematology, Cilt: 26 - Sayı: 3, 123–128. https://ajindex.com/articles/413367

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (20)

  1. Shehata N, Burrows R, Kelton JG. Gestational thrombocytopenia. Clin Obstet Gynecol 1999;42:327-34
  2. Sullivan CA, Martin JN. Management of the obstetric patient with thrombocytopenia. Clin Obstet Gynecol 1995;38:521-34
  3. Boehlen F, Hohlfeld P, Extermann P, Perneger TV, de Moerloose P. Platelet count at term pregnancy: a reappraisal of the threshold. Obstet Gynecol 2000;95:29
  4. Kam PC, Thompson SA, Liew AC. Review article: thrombocytopenia in the parturient. Anaesthesia 2004;59:255-64
  5. Cunningham FG, Gant NF, Leveno KJ, Gilstrap LC III, Hauth JC, Wenstrom KD, editors. Williams Obstetrics. 21st ed. New York: McGraw-Hill, 2001: 1307-38
  6. Shehata N, Burrow RF, Kelton JG. Gestational thrombocytopenia. Clin Obstet Gynecol 1999;42:327-3 7. Cines DG, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med 2002;346:13-25
  7. Lain KY, Roberts JM. Contemporary concepts of the pathogenesis and management of preeclampsia. J Am Med Assoc 2002;287:3183-6
  8. Burrows RF, Kelton JG. Neonatal thrombocytopenia and its relation to maternal thrombocytopenia. N Engl J Med 1993;329:1436–66
  9. Giles C. The platelet count and mean platelet volume. Br J Haematol 1981;48:31-7
  10. Tygart SG, McRoyan DK, Spinnato JA, McRoyan CJ, Kitay DZ. Longitudinal study of platelets indices during normal pregnancy. Am J Obstet Gynecol 1986;154:883-7
  11. Burrows RF, Kelton JG. Incidentally detected thrombocytopenia in healthy mothers and their infants. N Engl J Med 1988;319:142-5
  12. Ahmed Y, van Iddeking B, Paul C, Sullivan MHF, Elder MG. Retrospective analysis of platelet number and volumes in normal pregnancy and in preeclampsia. Br J Obstet Gynaecol 1993;100:216-20
  13. Sill PR, Lind T, Walker W. Platelet values during normal pregnancy. Br J Obstet Gynaecol 1985;92:480-3
  14. Beutler E, Lichtman MA, Coller BS, Kipps TJ, Seligsohn U, editors. Williams Hematology, 6th ed. Vol
  15. New York: McGraw-Hill, 2001
  16. Sainio S, Kekomäki R, Riikonen S, Teramo K. Maternal thrombocytopenia at term: a population-based study. Acta Obstet Gynecol Scand 2000;79:744-9
  17. Levy JA, Murphy LD. Thrombocytopenia in pregnancy, clinical review. J Am Board Fam Pract 2002;15:290-7
  18. Lewis SM, Bain BJ, Bates I. Dacie and Lewis Practical Haematology. 10th ed. London: Churchill Livingstone, 2006
  19. Dawson B, Trapp RG. Basic and Clinical Biostatistics. 4th ed. New York: McGraw-Hill, 2004: 72-5
  20. Silver R, Berkowitz R, Bussel J. Practice bulletin No. 6: Thrombocytopenia in pregnancy. Chicago