Journals / Turkish Journal of Hematology / 2009 / Cilt: 26 - Sayı: 3

Malignitesi olan kadınlarda doğurganlığın korunması-1: Nedenler, klinik gereksinimler ve endikasyonlar

Fertility preservation in females with malignant disease-1: Causes, clinical needs and indications

Pages
106–113
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, cryopreservation of gametes and gonads with fertility preservation options and indications prior to cancer treatments are discussed

📌 3 Key Takeaways

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Objective & Hypothesis:Cancer incidence is progressively increasing in parallel with an increase in the rate of cancer survivors with the help of advanced treatment modalities.
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Key Findings & Data:By the year 2010, it is estimated that one in every 250 persons will have survived a childhood malignancy.
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Conclusion & Impact:In this review, cryopreservation of gametes and gonads with fertility preservation options and indications prior to cancer treatments are discussed
🔬Design:Review & Systematic Survey
📍Scope:2010 Verileri
⚙️Variables:Kemoterapi · adjuvan · Kriyoprezervasyon

Abstract

Cancer incidence is progressively increasing in parallel with an increase in the rate of cancer survivors with the help of advanced treatment modalities. By the year 2010, it is estimated that one in every 250 persons will have survived a childhood malignancy. The increased rates of survival bring about complications related to reproductive health. Cytotoxic treatments due to chemo- and radiotherapy or bone marrow transplantation suppress or irreversibly harm not only female ovarian reserve but also male testicular sperm production. In this review, cryopreservation of gametes and gonads with fertility preservation options and indications prior to cancer treatments are discussed

Özet

Kanser insidansındaki artışa paralel olarak, gelişen tedavi modalitelerinin yardımıyla, bu hastalıktan sağkalım oranları da her geçen gün artmaktadır. 2010 yılında her 250 kişiden birinin çocukluk çağı kanserlerinden tedavi olmuş bir birey olacağı hesaplanmaktadır. Sağkalım oranlarının artışı, üreme sağlığını etkileyen komplikasyonları da beraberinde getirmektedir. Yüksek kemoterapi ve radyoterapi ya da kemik iliği transplantasyonuna bağlı sitotoksik tedaviler gerek over rezervini, gerekse testiküler sperm üretimini baskılayan ya da geri dünüşümsüz olarak hasara uğratan tedavi seçenekleridir. Bu derlemede, bahsedilen tedaviler öncesinde hastaların gonad ya da gametlerinin kriyoprezervasyonu ve kür sonrası fertilitenin geri kazandırılmasıyla ilgili seçenekler ve endikasyonlar ele alınmıştır.

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Cite This Article

SÖNMEZLER, M., ÖZKAVUKCU, İ. S. (2009). Malignitesi olan kadınlarda doğurganlığın korunması-1: Nedenler, klinik gereksinimler ve endikasyonlar. Turkish Journal of Hematology, Cilt: 26 - Sayı: 3, 106–113. https://ajindex.com/articles/413365

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