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Journals / Turkish Journal of Hematology / 2014 / Cilt: 31 - Sayı: 1

Stereotaktik Beyin Biyopsisi ile Tanı Koyulan T-hücreli Prolenfositik Löseminin Santral Sinir Sistemi Tutulumu: Olgu Sunumu

Central Nervous System Involvement of T-cell Prolymphocytic Leukemia Diagnosed with Stereotactic Brain Biopsy: Case Report

Selçuk GÖÇMEN
Murat KUTLAY
Alev ERİKÇİ
CEM ATABEY
Özkan SAYAN
Aptullah HAHOLU
Pages
75–78
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We emphasize the importance of rapid diagnosis and immediate treatment for patients presenting with CnS involvement and a history of leukemia or lymphoma

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Prolymphocytic leukemia (PLL) is a generalized malignancy of the lymphoid tissue characterized by the accumulation of monoclonal lymphocytes, usually of B cell type.
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Key Findings & Data:Involvement of the central nervous system (CnS) is an extremely rare complication of T-cell prolymphocytic leukemia (T-PLL).
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Conclusion & Impact:We emphasize the importance of rapid diagnosis and immediate treatment for patients presenting with CnS involvement and a history of leukemia or lymphoma
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Prolymphocytic leukemia (PLL) is a generalized malignancy of the lymphoid tissue characterized by the accumulation of monoclonal lymphocytes, usually of B cell type. Involvement of the central nervous system (CnS) is an extremely rare complication of T-cell prolymphocytic leukemia (T-PLL). We describe a case of T-PLL presenting with symptomatic infiltration of the brain that was histopathologically proven by stereotactic brain biopsy. We emphasize the importance of rapid diagnosis and immediate treatment for patients presenting with CnS involvement and a history of leukemia or lymphoma

Özet

Prolenfositik lösemi (PLL), genellikle B hücre tipi monoklonal lenfositlerin birikimi ile karakterize lenfoid dokunun genel malign bir hastalığıdır. Santral sinir sistemi (SSS) tutulumu T-hücreli Prolenfositik löseminin (T-PLL) çok nadir görülen bir komplikasyonudur. Biz, beyinin semptomatik infiltrasyonu ile ortaya çıkan, stereotaktik beyin biopsisi ile tanı koyulmuş T-PLL'li bir olgu sunuyoruz. Geçmişte lösemi veya lenfoma nedeni ile tedavi edilmiş ve SSS tutulumu ile başvuran hastalar için, hızlı tanı ve acil tedavinin önemini açıkladık

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Cite This Article

GÖÇMEN, S., KUTLAY, M., ERİKÇİ, A., ATABEY, C., SAYAN, Ö., HAHOLU, A. (2014). Stereotaktik Beyin Biyopsisi ile Tanı Koyulan T-hücreli Prolenfositik Löseminin Santral Sinir Sistemi Tutulumu: Olgu Sunumu. Turkish Journal of Hematology, Cilt: 31 - Sayı: 1, 75–78. https://ajindex.com/articles/413304

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References (10)

  1. Kuwabara H, Kanamori H, Takasaki H, Takabayashi M, Yamaji S, Tomita N, Fujimaki K, Fujisawa S, Ishigatsubo Y. Involvement of central nervous system in prolymphocytoid transformation of chronic lymphocytic leukemia. Leuk Lymphoma 2003;44:1235-1237
  2. Garderet L, Bittencourt H, Kaliski A, Daniel M, Ribaud P, Socié G, Gluckman E. Treatment of T-prolymphocytic leukemia with nonmyeloablative allogeneic stem cell transplantation. Eur J Haematol 2001;66:137-139
  3. Pamuk GE, Puyan FO, Unlü E, Oztürk E, Demir M. The first case of de novo B-cell prolymphocytic leukemia with central nervous system involvement: description of an unreported complication. Leuk Res 2009;33:864-867
  4. Wang ML, Shih LY, Dunn P, Kuo MC. Meningeal involvement in B-cell chronic lymphocytic leukemia: report of two cases. J Formos Med Assoc 2000;99:775-778
  5. Brito-Babapulle F, Huang D, Lavender P, Galton D, Catovsky D. Regression of intracerebral lesions in T prolymphocytic leukaemia treated with intravenous deoxycoformycin. Eur J Haematol 1988;40:185-187
  6. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW. WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. 4th ed. Lyon, France: IARC, 2008:270
  7. Denier C, Tertian G, Ribrag V, Lozeron P, Bilhou-Nabera C, Lazure T, Abbed K, Lacroix C, Adams D. Multifocal deficits due to leukemic meningoradiculitis in chronic lymphocytic leukemia. J Neurol Sci 2009;277:130-302
  8. Aker FV, Hakan T, Karadereler S, Erkan M. Accuracy and diagnostic yield of stereotactic biopsy in the diagnosis of brain masses: comparison of results of biopsy and resected surgical specimens. Neuropathology 2005;25:207-213
  9. Schwartz TH, Sisti MB. Stereotactic biopsy. In: Sekhar LN, Fessler RG, editors. Atlas of Neurosurgical Techniques: Brain. 1st ed. New York, Thieme, 2006;422-428
  10. Air EL, Leach JL, Warnick RE, McPherson CM. Comparing the risks of frameless stereotactic biopsy in eloquent and noneloquent regions of the brain: a retrospective review of 284 cases. J Neurosurg 2009;111:820-824. 11.Greenberg MS. Handbook of Neurosurgery. 6th ed. New York, Thieme, 2006;545. 12.Dammers R, Haitsma IK, Schouten JW, Kros JM, Avezaat CJ, Vincent AJ. Safety and efficacy of frameless and frame-based intracranial biopsy techniques. Acta Neurochir (Wien) 2008;150:23-29. 13.Kongkham PN, Knifed E, Tamber MS, Bernstein M. Complications in 622 cases of frame-based stereotactic biopsy, a decreasing procedure. Can J Neurol Sci 2008;35