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Journals / Turkish Journal of Hematology / 2008 / Cilt: 25 - Sayı: 2

Kök hücrelerinin sınıflandırılması ve isimlendirilmesine ilişkin kısa bir derleme

A concise review on the classification and nomenclature of stem cells

ALP CAN
Pages
57–59
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, the aim of this brief review is to give a conceptual approach to classifying the stem cells beginning from the early morula stage totipotent embryonic stem cells to the unipotent tissue-resident adult stem cells, also called tissue-specific stem cells.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Stem cell biology and regenerative medicine is a relatively young field.
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Key Findings & Data:However, in recent years there has been a tremendous interest in stem cells possibly due to their therapeutic potential in disease states.
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Conclusion & Impact:Therefore, the aim of this brief review is to give a conceptual approach to classifying the stem cells beginning from the early morula stage totipotent embryonic stem cells to the unipotent tissue-resident adult stem cells, also called tissue-specific stem cells.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Embriyonik kök hücreler · Sınıflandırma · Teminoloji

Abstract

Stem cell biology and regenerative medicine is a relatively young field. However, in recent years there has been a tremendous interest in stem cells possibly due to their therapeutic potential in disease states. As a classical definition, a stem cell is an undifferentiated cell that can produce daughter cells that can either remain a stem cell in a process called self-renew¬al, or commit to a specific cell type via the initiation of a differentiation pathway leading to the production of mature progeny cells. Despite this acknowledged definition, the classification of stem cells has been a perplexing notion that may often raise misconception even among stem cell biologists. Therefore, the aim of this brief review is to give a conceptual approach to classifying the stem cells beginning from the early morula stage totipotent embryonic stem cells to the unipotent tissue-resident adult stem cells, also called tissue-specific stem cells.

Özet

Kök hücresi biyolojisi ve onarımsal tıp görece yeni alanlardır. Buna karşın, son yıllarda çeşitli hastalıklarda tedavi amacıyla kullanılabilme potansiyelleri nedeniyle kök hücrelerine olağanüstü bir ilgi artışı vardır. Klasik tanımıyla kök hücresi, kendini yenileme adı verilen mekanizmayla farklılaşmadan kendini çoğaltan veya bir dizi farklılaşma aşamasından geçerek olgun hücrelere dönüşebilen hücrelerdir. Çok kabul gören bu tanımlamaya karşın, kök hücrelerin sınıflandırması karmaşık olup alanın uzmanlarınca bile çoğu zaman kavram kargaşasına neden olmaktadır. Bu kısa derlemenin amacı, morula aşamasındaki totipotent embriyonik kök hücrelerinden başlayıp dokuda yerleşik olan ve dokuya özgü kök hücresi olarak adlandırılan unipotent hücrelere varan bir yelpazade kök hücrelerini sınıflandırmada kullanılan kriterleri kavramsal olarak özetlemektir.

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Cite This Article

CAN, A. (2008). Kök hücrelerinin sınıflandırılması ve isimlendirilmesine ilişkin kısa bir derleme. Turkish Journal of Hematology, Cilt: 25 - Sayı: 2, 57–59. https://ajindex.com/articles/413201

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