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Journals / Turkish Journal of Hematology / 2012 / Cilt: 29 - Sayı: 4

Steroid dirençli gastrointestinal graft versus host hastalığında intramezenterik steroid uygulaması

Intramesenteric steroid treatment for steroid- refractory gastrointestinal graft versus host disease

Aynur BİLGİN UĞUR
PERVİN TOPÇUOĞLU
Tanzer SANCAK
Nahide KONUK
Mutlu ARAT
Pages
409–412
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, intra-arterial steroid injection might be an alternative treatment approach for steroid-refractory GI GVHD.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Currently, steroid-refractory severe gastrointestinal (GI) graft versus host disease (GVHD) is among the most important complications of allogeneic transplantation, and as yet there is no standard approach to its treatment.
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Key Findings & Data:Herein we report two cases with steroid-refractory GI GVHD that received intramesenteric steroid treatment.
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Conclusion & Impact:In conclusion, intra-arterial steroid injection might be an alternative treatment approach for steroid-refractory GI GVHD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Currently, steroid-refractory severe gastrointestinal (GI) graft versus host disease (GVHD) is among the most important complications of allogeneic transplantation, and as yet there is no standard approach to its treatment. Herein we report two cases with steroid-refractory GI GVHD that received intramesenteric steroid treatment. In both cases the frequency and volume of diarrhea resolved completely following intramesenteric methylprednisolone (MP) injection. In conclusion, intra-arterial steroid injection might be an alternative treatment approach for steroid-refractory GI GVHD.

Özet

Günümüzde, steroid dirençli gastrointestinal (Gİ) graft versus host hastalığı (GvHH) allogeneik transplantasyon yapılan hastalarda izlenen en sık komplikasyonlardan biridir ve henüz standart bir tedavi yaklaşımı yoktur. Burada, steroid refrakter GvHH olan iki vakanın intramezenterik steroid uygulamasına dair sonuçları bildirilmiştir. Her iki hastada intramezenterik metilprednizolon (MP) enjeksiyonunu takiben diarenin sıklığı ve miktarı tamamen düzelmiştir. Sonuç olarak, intra-arteriel steroid verilimi bu tip olgularda alternative bir tedavi yaklaşımı olabilir.

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Cite This Article

UĞUR, A. B., TOPÇUOĞLU, P., SANCAK, T., KONUK, N., ARAT, M. (2012). Steroid dirençli gastrointestinal graft versus host hastalığında intramezenterik steroid uygulaması. Turkish Journal of Hematology, Cilt: 29 - Sayı: 4, 409–412. https://ajindex.com/articles/413145

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References (5)

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