Journals / Turkish Journal of Hematology / 2001 / Cilt: 18 - Sayı: 2

Epstein-Barr Virus latent membrane protein 1 (LMP-1) in Hodgkin's lymphoma patients in Turkey

Pages
123–126
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results of the current study suggests a strong association of Epstein-Barr virus with Hodgkin's lymphoma in Turkey and, together with those reported previously showed that Epstein-Barr virus correlated with mixed cellular type, with a slight male predominancy while there was no correlation with age.

📌 3 Key Takeaways

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Objective & Hypothesis:Epstein-Barr virus (EBV) has been implicated as a contributing factor in the development of Hodgkin's lymphoma.
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Key Findings & Data:The aim of this study was to elucidate the association of Hodgkin's lymphoma with EBV in a Turkish population using immunohistochemical detection of LMP-1.
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Conclusion & Impact:The results of the current study suggests a strong association of Epstein-Barr virus with Hodgkin's lymphoma in Turkey and, together with those reported previously showed that Epstein-Barr virus correlated with mixed cellular type, with a slight male predominancy while there was no correlation with age.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Viral matriks proteinleri · Türkiye · Epstein-barr virüs enfeksiyonları

Özet

Epstein-Barr virus (EBV) has been implicated as a contributing factor in the development of Hodgkin's lymphoma. The aim of this study was to elucidate the association of Hodgkin's lymphoma with EBV in a Turkish population using immunohistochemical detection of LMP-1. We studied a total of 21 consecutive cases of Hodgkin's lymphoma from Turkey. LMP-1 protein was detected in 9 of 21 (42.8%) cases. LMP-1 was positive in 4 of 7 (57%) mixed cellularity and 5 of 13 (38.4%) nodular sclerosis subtype. The results of the current study suggests a strong association of Epstein-Barr virus with Hodgkin's lymphoma in Turkey and, together with those reported previously showed that Epstein-Barr virus correlated with mixed cellular type, with a slight male predominancy while there was no correlation with age.

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Cite This Article

ATAOĞLU, Ö., FEN, T., SÜER, Ö., DAĞLI, M., AKI, Z., YAMAÇ, K. (2001). Epstein-Barr Virus latent membrane protein 1 (LMP-1) in Hodgkin's lymphoma patients in Turkey. Turkish Journal of Hematology, Cilt: 18 - Sayı: 2, 123–126. https://ajindex.com/articles/413056

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