Journals / Turkish Journal of Hematology / 2002 / Cilt: 19 - Sayı: 2

Trace element analyses (Zinc and selenium) in pediatric malignant lymphomas

Pages
239–244
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Supplemention of the patients with physiological doses of Zn and Se, in addition to standard chemo radiotherapy regimen was proposed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Ninetysix untreated patients with Malignant lymphoma's, 81 Hodgkin's disease and 15 Burkitt's lymphoma were studied for zinc (Zn) and selenium (Se) status.
📊
Key Findings & Data:Plasma and hair Zn, and Se levels were measured by atomic absorption spectrophotometry.
💡
Conclusion & Impact:Supplemention of the patients with physiological doses of Zn and Se, in addition to standard chemo radiotherapy regimen was proposed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lenfom · Eser elementler · Çinko

Özet

Ninetysix untreated patients with Malignant lymphoma's, 81 Hodgkin's disease and 15 Burkitt's lymphoma were studied for zinc (Zn) and selenium (Se) status. Plasma and hair Zn, and Se levels were measured by atomic absorption spectrophotometry. Chronic Zn and Se deficiencies (low plasma and low hair Zn and Se levels together) were found to be associated with Malignant lymphoma's in Turkish children. This was most likely due to poor "nutritional environment" of the patients since majority of the Malignant lymphoma cases were from low socioeconomic class. Supplemention of the patients with physiological doses of Zn and Se, in addition to standard chemo radiotherapy regimen was proposed.

🔖

Cite This Article

ÇAVDAR, A. O., ÜNAL, E., BABACAN, E., GÖZDAŞOĞLU, S., YAVUZ, G., MENGÜBAŞ, K., PAMİR, A., TAÇYILDIZ, N. (2002). Trace element analyses (Zinc and selenium) in pediatric malignant lymphomas. Turkish Journal of Hematology, Cilt: 19 - Sayı: 2, 239–244. https://ajindex.com/articles/412987

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Çavdar AO, Babacan E, Ertem U, Gözdaşoğlu S, Ar- casoy A. Zinc status and cellular immunity in pediatric Hodgkin's disease. In: Prasad AS, Çavdar AO, Brewer GJ, Agget PS (eds). Zinc Deficiency in Human Subjects. NewYork: Alan R Liss, 1983:207-17
  2. Donma MM, Donma O, Taş MA. Hair, zinc and cop¬ per concentrations and zinc: Copper ratios in pedi¬ atric malignancies and healthy children from S. Central Turkey. Biol Trace Elem Research 1990; 36:51-63
  3. Denis J, Malvy M, Arnaud J, Burtschy B, Sommelet D, Leverger G, Dostalova L, Manesme OA. Antioxi- dant micronutrients and childhood malignancy du¬ ring oncological treatment. Med Ped Oncol 1997; 29:213-7
  4. Gözdaşoğlu S, Akar N, Çavdar AO, Babacan E. Serum copper and zinc values and copper/zinc ratio in acute leukemia and relation to prognosis. 1981 Intern Istanbul Symposia on Hematology 1981:491-501
  5. Saha S, Mark GC, Hartel GF, Ferguson EL. Zinc status, growth and respiratory disease in Australia preschool children. In: Research Abdullah M, Bost M, Arnaud P, G. Chazot (eds). New Aspects in Trace Element. Smith-gordon, 1999:68-75
  6. Çavdar AO, Yavuz G, Babacan E, et al. Burkitt's lymphoma in Turkish children: Clinical, viral (EBV) and molecular studies. Leuk-Lymphoma 1994; 14: 323-30
  7. Mocchegiani E, Paolucci P, Granchi D, Cavallazzi L, Santarelli L, Fabris N. Plasma zinc level and thymic hormone activity in young cancer patients. Blood. 1994;83:749-57
  8. Babacan E, Çavdar AO, Arcasoy A. Serum zinc le¬ vels, lymphocyte counts and functions in pediatric Hodgkin's disease. Boll 1st Sieroter Milanese 1977; 56:228-34
  9. Çavdar AO, Babacan E, Gözdaşoğlu S, et al. Zinc and anergy in pediatric Hodgkin's disease in Turkey. Cancer 1987;59:305-10
  10. Çavdar AO, Babacan E, Ünal E, Gözdaşoğlu S, et al. Zinc status in pediatric Hodgkin's disease in Turkey: Possible impact on the immune system. J Trace Elem Exp Med 1997;10:191-6. 10a. Şahin G, Ertem U, Duru F, Birgen D, Yüksek N. High prevelance of chronic magnesium deficiency in T-cell lymphoblestic leukemia and chronic zinc deficiency in children with acute lymphoblastic leukemia and malignant lymphoma. Leukemia and Lyphoma 2000;39:555-62
  11. Çavdar AO, Pamir A. Gözdaşoğlu S, et al. Hodgkin's disease in children. Clinicoepidemiologic and viral (Epstein-Barr virus) analyses. Med & Ped Oncology 1999;32:18-23
  12. Ertem J, Arcasoy A, Çavdar AO, Cin Ş. Hair zinc levels in healthy and malnourished children. Am J Clin Nutr 1978;31:1172-4
  13. Çavdar AO, Arcasoy