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AI Summary & Key Takeaways
AI Insight⚡ TL;DR(Too Long; Didn't Read)
The clinical spectrum is wide and immunophenotyping and genotyping studies need to make a diagnosis
📌 3 Key Takeaways
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Objective & Hypothesis:We presented a 64-year-old male patient with T-large granular cell leukemia/lymphoma with an agressive clinical course.
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Key Findings & Data:The phenotyping of the cells was typical T-cell lineage [CD2 (+), CD3 (+), CD5 (+)].
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Conclusion & Impact:The clinical spectrum is wide and immunophenotyping and genotyping studies need to make a diagnosis
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Lenfom · Lösemi · T hücreli
Özet
We presented a 64-year-old male patient with T-large granular cell leukemia/lymphoma with an agressive clinical course. Large granular lymphocytes were noted on peripheral blood smear. The phenotyping of the cells was typical T-cell lineage [CD2 (+), CD3 (+), CD5 (+)]. Clonal rearrangement of the T-cell receptor gene (TCR) was demonstrated by DNA hybridization technique. Large granular cell leukemia/lymphoma is a distinct entity with spesific clinicobiological aspects. The clinical spectrum is wide and immunophenotyping and genotyping studies need to make a diagnosis
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Cite This Article
TÜRKEN, O., ÖZTÜRK, A., ORHAN, B., KANDEMİR, G., YAYLACI, M. (2002). A case report: Large granular cell leukemia / lymphoma (LGL). Turkish Journal of Hematology, Cilt: 19 - Sayı: 4, 473–476. https://ajindex.com/articles/412973