Siklosporin ile başarılı şekilde tedavi edilen kazanılmış saf megakaryositik aplazi

Treatment with prednisone and intravenous immunoglobulin failed, but he was successfully treated with cyclosporine, with complete remission after 90 days and normal platelet count maintained thereafter.

📌 3 Key Takeaways

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Objective & Hypothesis:Acquired pure megakaryocytic aplasia is a rare hematological disorder characterized by thrombocytopenia with absent or markedly reduced megakaryocytes in the bone marrow.

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Key Findings & Data:We report a case of a 25-year-old male diagnosed as acquired pure megakaryocytic aplasia.

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Conclusion & Impact:Treatment with prednisone and intravenous immunoglobulin failed, but he was successfully treated with cyclosporine, with complete remission after 90 days and normal platelet count maintained thereafter.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Acquired pure megakaryocytic aplasia is a rare hematological disorder characterized by thrombocytopenia with absent or markedly reduced megakaryocytes in the bone marrow. We report a case of a 25-year-old male diagnosed as acquired pure megakaryocytic aplasia. Treatment with prednisone and intravenous immunoglobulin failed, but he was successfully treated with cyclosporine, with complete remission after 90 days and normal platelet count maintained thereafter.

Özet

Kazanılmış saf megakaryositik aplazi, kemik iliğinde namevcut ya da anlamlı ölçüde azaltılmış megakaryosit içeren trombositopeni ile karakterize, nadir hematolojik bir hastalıktır. Kazanılmış saf megakaryositik aplazi teşhisi konmuş, prednizon ve intravenöz immunoglobulin ile tedavisi başarısız olmuş ve siklosporin ile başarılı biçimde tedavi edilerek 90 gün sonra tam remisyona ulaşan ve ondan sonra platelet sayımı normalleşen 25 yaşında erkek bir olgunun raporu sunulmuştur.

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Cite This Article

OMRI, H. E., İBRAHIM, F., TAHA, R. Y., NEGM, R. H., KHINJI, A. A., YASSIN, M., HAJJI, İ. A., AYOUBI, H. E., BADEN, H. (2010). Siklosporin ile başarılı şekilde tedavi edilen kazanılmış saf megakaryositik aplazi. Turkish Journal of Hematology, Cilt: 27 - Sayı: 4, 289–293. https://ajindex.com/articles/412955

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