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Journals / Turkish Journal of Hematology / 2013 / Cilt: 30 - Sayı: 2

Hidroksiüre’nin anlatılmamış hikayesi: Bacak ülserli 3 olgunun tedavisi

Successful management of Hydroxyurea-induced Leg ulcers in essential thrombocythemia: Report of 3 cases

Jihane Abou RAHAL
S. Rim ISHAK
K. Zaher OTROCK
E. Joseph MAAKARON
Samer GHOSN
T. Ali TAHER
Pages
184–187
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Awareness of this important treatment complication is important to avoid the pitfall of futile invasive interventions.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Essential thrombocythemia is one of the myeloproliferative neoplasms with a plethora of thrombohemorrhagic complications.
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Key Findings & Data:We herein report 3 patients with essential thrombocythemia treated with hydroxyurea who developed refractory leg ulcers, and we outline their successful management.
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Conclusion & Impact:Awareness of this important treatment complication is important to avoid the pitfall of futile invasive interventions.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Essential thrombocythemia is one of the myeloproliferative neoplasms with a plethora of thrombohemorrhagic complications. Hydroxyurea has been proven to be an effective treatment for this condition. However, it is not without side effects. We herein report 3 patients with essential thrombocythemia treated with hydroxyurea who developed refractory leg ulcers, and we outline their successful management. We also review the literature to shed light on the mechanism of this toxicity. Awareness of this important treatment complication is important to avoid the pitfall of futile invasive interventions.

Özet

Esansiyel trombositoz, trombohemorajik komplikasyonların sık görüldüğü miyeloproliferatif hastalıklardan biridir. Hidroksiürenin bu durum için etkili bir tedavi olduğu kanıtlanmıştır. Bununla birlikte, yan etkisiz değildir. Bu makalede refrakter bacak ülserleri gelişen 3 esansiyel trombositoz hastasında hidroksiüre ile başarılı şekilde gerçekleştirilen tedavi sürecini bildiriyoruz. Aynı zamanda, bu toksisitenin mekanizmasına ışık tutacak literatür gözden geçirilmiştir. Bu önemli komplikasyonun farkında olmak, gereksiz invaziv girişimlerden kaçınmak için önemlidir.

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Cite This Article

RAHAL, J. A., ISHAK, S. R., OTROCK, K. Z., MAAKARON, E. J., GHOSN, S., TAHER, T. A. (2013). Hidroksiüre’nin anlatılmamış hikayesi: Bacak ülserli 3 olgunun tedavisi. Turkish Journal of Hematology, Cilt: 30 - Sayı: 2, 184–187. https://ajindex.com/articles/412856

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