Journals / Turkish Journal of Hematology / 2012 / Cilt: 29 - Sayı: 1

Influenza A (H1N1) infeksiyonu allojeneik nakil hastalarında nasıl seyrediyor?

How does influenza A (H1N1) infection proceed in allogeneic stem cell transplantation recipients?

Pages
63–66
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The course of swine flu can vary and progress with bacterial or other viral infections in immunosuppressed patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The clinical course of influenza A (H1N1) infection in allogeneic hematopoietic stem cell transplantation (AHSCT) recipients is not clearly known.
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Key Findings & Data:We report 3 AHSCT recipients that were infected with influenza A (H1N1).
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Conclusion & Impact:The course of swine flu can vary and progress with bacterial or other viral infections in immunosuppressed patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The clinical course of influenza A (H1N1) infection in allogeneic hematopoietic stem cell transplantation (AHSCT) recipients is not clearly known. We report 3 AHSCT recipients that were infected with influenza A (H1N1). Each of the patients had a different hematological disease and was at a different post-transplantation stages. All the patients were treated with oseltamivir, and zanamivir was switched to oseltamivir in 1 patient. All the patients survived without any complications. The course of swine flu can vary and progress with bacterial or other viral infections in immunosuppressed patients.

Özet

H1N1 virüsünün allojeneik kök hücre nakli yapılan Hematoloji hastalarında kliniği ve seyri konusunda veriler oldukça yetersizdir. Biz bu olgu serisinde, Ankara Üniversitesi Tıp Fakültesi kök hücre nakli ünitesinde allojeneik nakil yapılmış ve Influenza A/ H1N1 infeksiyonu saptanmış 3 olgumuzu tartıştık. Üç hastamızın da farklı hematolojik malignite tanıları vardı ve nakilin farklı evrelerinde olan hastalardı. Tüm hastalara oseltamivir tedavisi verildi; bir hastada zanamivir tedavisine geçilmesi gerekti. Hastaların üçü de herhangi bir komplikasyon kalmadan tam iyileşme sağlanarak taburcu edildi. Influenza A/H1N1’e bağlı grip immunsupresif hasta gruplarında farklı seyirler gösterebilmekte, bakteriyel ve viral enfeksiyonlarla birlikte seyredebilmektedir.

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Cite This Article

CİVRİZ, S. B., BOZKURT, G., TOPÇUOĞLU, P., AZAP, A., ÖZCAN, M., KONUK, N., ARSLAN, Ö. (2012). Influenza A (H1N1) infeksiyonu allojeneik nakil hastalarında nasıl seyrediyor?. Turkish Journal of Hematology, Cilt: 29 - Sayı: 1, 63–66. https://ajindex.com/articles/412674

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References (1)

  1. Whimbey E, Elting LS, Couch RB, et al: Influenza A virus infections among hospitalized adult bone marrow transplant recipients. Bone Marrow Transplant 1994; 13 (4): 437-440 2. Kharfan Dabaja MA, Velez A, Richards K, Greene J, Field T, Sandin R: Influenza A/pandemic 2009/H1N1in the setting of allogeneic hematopoietic stem cell transplantation: A potentially catastrophic problem in a vulnerable population. Int J Hematol 2010; 91 (1): 124-127 3. Weinstock DM, Gubareva LV, Zuccotti G: Prolonged shedding of multidrug resistant Influenza A virus in an immuncomprimised patient. N Eng J Med 2003; 348: 867-868 4. Casper C, Englund J, Boeckh M: How I treat influenza in patients with hematologic malignancies. Blood 2010; 115 (7): 1331-1342 5. Hajjar LA, Mauad T, Galas FR, Kumar A, da Silva LF, Dolhnikoff M, Trielli T, Almeida JP, Borsato MR, Abdalla E, Pierrot L, Filho RK, Auler JO Jr, Saldiva PH, Hoff PM: Severe novel Influenza A (H1N1) infection in cancer patients. Ann Oncol 2010; 21 (12): 2333-2341 6. Redelman-Sidi G, Sepkowitz KA, Huang CK, Park S, Stiles J, Eagan J, Perlin DS, Pamer EG, Kamboj M: 2009 H1N1 infection in cancer patients and hematopoietic stem cell transplant recipients. J Infect 2010; 60: 257-263 7. Avetisyan G, Aschan J, Hassan M, Ljungman P: Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation. Transplantation 2008; 86 (2): 257-263 8. Engelhard D,Nagler A,Hardan I: Antibody response to a two dose regimen of influenza vaccine in allogeneic T cell depleted and autologus BMT recipients. Bone Marrow Transplant 1993; 11: 1-5 9. Yalçın SS, Kondolot M, Albayrak N, Altaş AB, Karacan Y, Kuşkonmaz B, Aksu S, Cetin M, Göker H, Yurdakök K, Uçkan D: Serological response to influenza vaccine after hematopoetic stem cell transplantation. Ann Hematol 2010; 89 (9): 913-918 10. Ditschkowski M, Elmaagacli AH, Beelen DW: H1N1 in allogeneic stem cell recipients: Courses of infection and influence of vaccination on graft versus host disease. Ann Hematol 2011; 90 (1): 117-118