Journals / Turkish Journal of Pediatrics / 2016 / Cilt: 58 - Sayı: 6

Parapharyngeal giant ganglioneuroma with multifocal bone involvement in a pediatric female patient

Pages
669–674
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, complete surgical excision of the tumor, if possible, is the treatment of choice with high success rate.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Salimov A, Süslü N, Kuşçu O, Süslü AE, Akyol MU, Gököz Ö, Özoğul E.
📊
Key Findings & Data:Turk J Pediatr 2016; 58: 669-674.Ganglioneuroma is a rare benign tumor that originates from neural crest.
💡
Conclusion & Impact:In conclusion, complete surgical excision of the tumor, if possible, is the treatment of choice with high success rate.
🔬Design:Research Article
📍Scope:2016 Verileri
⚙️Variables:Domain Parameters

Özet

Salimov A, Süslü N, Kuşçu O, Süslü AE, Akyol MU, Gököz Ö, Özoğul E. Parapharyngeal giant ganglioneuroma with multifocal bone involvement in a pediatric female patient. Turk J Pediatr 2016; 58: 669-674.Ganglioneuroma is a rare benign tumor that originates from neural crest. Tumor tends to be slow growing, asymptomatic but can cause symptoms because of pressure to neighboring structures. In the head and neck region they are relatively rarely seen. We hereby present a rare case of multiple ganglioneuromas that were located in parapharyngeal space, iliac bone and other bones in a 13-year-old girl. Patient underwent surgery for the excision of a large mass, extending from parapharyngeal space to neck, with transparotid and transcervical combined approach. After operation, MIBG (iodine-123meta-iodobenzylguanidine) scintigraphy was performed and involvement of parietooccipital bone, lumbal vertebra, right iliac wing medial cortex and left humerus were detected. No adjuvant therapy was given to the patient. There is no evidence of recurrence in the head and neck region in the following 12 months. In conclusion, complete surgical excision of the tumor, if possible, is the treatment of choice with high success rate. Close clinical and radiological follow-up for these tumors after surgery should be made

🔖

Cite This Article

SALİMOV, A., SÜSLÜ, N., KUŞCU, O., SÜSLÜ, A. E., AKYOL, M. U., GÖKÖZ, Ö., ÖZOĞUL1, E. (2016). Parapharyngeal giant ganglioneuroma with multifocal bone involvement in a pediatric female patient. Turkish Journal of Pediatrics, Cilt: 58 - Sayı: 6, 669–674. https://ajindex.com/articles/412205

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Cavanaugh DA, Jawahar A, Harper J, McLaren BK, Wooten T, Kerr EJ. Cervical ganglioneuroma in an adult man: case report and literature review of a rare occurrence. J La State Med Soc 2010; 162: 218-221.
  2. Kaufman MR, Rhee JS, Fliegelman LJ, et al. Ganglioneuroma of the parapharyngeal space in a pediatric patient. Otolaryngol Head Neck Surg 2001; 124: 702-704.
  3. Müller A, Förster G, Behrendt W, Kosmehl H. Headache as an unusual presenting symptom of retropharyngeal ganglioneuroma. Acta Otolaryngol 2002; 122: 565-568.
  4. Ma J, Liang L, Liu H. Multiple cervical ganglioneuroma: A case report and review of the literature. Oncol Lett 2012; 4: 509-512.
  5. Hallur N, Sikkerimath BC, Gudi SS, Chour G, Ginimav S, Nidoni MJ. Parapharyngeal ganglioneuroma of hypoglossal nerve in a 4-year-old girl: A rare case report. Maxillofac Oral Surg 2012; 11: 343-346.
  6. Geoerger B, Hero B, Harms D, et al. Metabolic activity and clinical features of primary ganglioneuromas. Cancer 2001; 91: 1905-1913.
  7. Lucas K, Gula MJ, Knisely AS, Virgi MA, Wollman M, Blatt J. Catecholamine metabolites in ganglioneuroma. Med Pediatr Oncol 1994; 22: 240-243.
  8. Pucci A, Pucci E, Santini F, et al. A ganglioneuroma with features of a thyroid nodule: Intense pain on fine needle biopsy as a diagnostic clue. Thyroid 2009; 19: 201-204.
  9. Albuquerque BS, Farias TP, Dias FL, Torman D. Surgical management of parapharyngeal ganglioneuroma: Case report and review of the literature. ORL J Otorhinolaryngol Relat Spec 2013; 75: 240-244.
  10. Lonergan GJ, Schwab CM, Suarez ES, Carlson CL. Neuroblastoma, ganglioneuroblastoma, and ganglioneuroma: Radiologic-pathologic correlation. Radiographics 2002; 22: 911-934.
  11. Ichikawa T, Ohtomo K, Araki T et al. Ganglioneuroma: Computed tomography and magnetic resonance features. Br J Radiol 1996; 69: 114-121.
  12. Ricci A, Jr, Parham DM, Woodruff JM, Callihan T, Green A, Erlandson RA. Malignant peripheral nerve sheath tumors arising from ganglioneuromas. Am J Surg Pathol 1984; 8: 19-29.
  13. Moschovi M, Arvanitis D, Hadjigeorgi C, Mikraki V, Tzortzatou-Stathopoulou F. Late malignant transformation of dormant ganglioneuroma? Med Pediatr Oncol 1997; 28: 377-381.
  14. Kulkarni AV, Bilbao JM, Cusimano MD, Muller PJ. Malignant transformation of ganglioneuroma into spinal neuroblastoma in an adult. Case report. J Neurosurg 1998; 88: 324-327.
  15. Chandrasoma P, Shibata D, Radin R, Brown LP, Koss M. Malignant peripheral nerve sheath tumor arising in an adrenal ganglioneuroma in an adult male homosexual. Cancer 1986; 57: 2022-2