The aim of this review is to highlight the clinical characteristicsand treatments of ON for pediatricians, focusing on optic neuritis.
📌 3 Key Takeaways
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Objective & Hypothesis:Optic neuropathy (ON) is a common problem in childhood resulting fromvarious causes including ischemic, metabolic, hereditary, traumatic andinflammatory events.
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Key Findings & Data:The latter represents the most prevalent group; the term“optic neuritis” is generally used for this group which can manifest as part ofa systemic inflammatory disease, a central nervous system disorder, or as anisolated entity.
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Conclusion & Impact:The aim of this review is to highlight the clinical characteristicsand treatments of ON for pediatricians, focusing on optic neuritis.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters
Özet
Optic neuropathy (ON) is a common problem in childhood resulting fromvarious causes including ischemic, metabolic, hereditary, traumatic andinflammatory events. The latter represents the most prevalent group; the term“optic neuritis” is generally used for this group which can manifest as part ofa systemic inflammatory disease, a central nervous system disorder, or as anisolated entity. The aim of this review is to highlight the clinical characteristicsand treatments of ON for pediatricians, focusing on optic neuritis.
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Cite This Article
GÜNBEY, C., KONUŞKAN, B. (2019). Optic neuropathies in childhood: a review of etiology and treatment. Turkish Journal of Pediatrics, Cilt: 61 - Sayı: 4, 471–476. https://ajindex.com/articles/412096
Biousse V, Newman NJ. Ischemic optic neuropathies. N Engl J Med 2015; 372: 2428-2436
Behbehani R. Clinical approach to optic neuropathies. Clin Ophthalmol 2007; 1: 233-246
The clinical profile of optic neuritis. Experience of the Optic Neuritis Treatment Trial. Optic Neuritis Study Group. Arch Ophthalmol 1991; 109: 1673-1678
Lapeyraque AL, Haddad E, Andre JL, et al. Sudden blindness caused by anterior ischemic optic neuropathy in 5 children on continuous peritoneal dialysis. Am J Kidney Dis 2003; 42: E3-E9
Kim JS, Deputy S, Vives MT, Aviles DH. Sudden blindness in a child with end-stage renal disease. Pediatr Nephrol 2004; 19: 691-693
Matalia J, Kasturi N, Anaspure HD, Shetty BK. Tonic pupil, anterior ischemic optic neuropathy in a teenager with Takayasu arteritis. Can J Ophthalmol 2013; 48: e159-e163
Partal A, Moshfeghi DM, Alcorn D. Churg-Strauss syndrome in a child: retina and optic nerve findings. Br J Ophthalmol 2004; 88: 971-972
Di Zazzo G, Guzzo I, De Galasso L, et al. Anterior ischemic optical neuropathy in children on chronic peritoneal dialysis: report of 7 cases. Perit Dial Int 2015; 35: 135-139
Hayati AA, Wan-Hitam WH, Cheong MT, Yunus R, Shatriah I. Optic neuritis in a child with biotinidase deficiency: case report and literature review. Clin Ophthalmol 2012; 6: 389-395
McAbee GN, Prieto DM, Kirby J, Santilli AM, Setty R. Permanent visual loss due to dietary vitamin A deficiency in an autistic adolescent. J Child Neurol 2009; 24: 1288-1289
Van Stavern GP. Metabolic, hereditary, traumatic, and neoplastic optic neuropathies. Continuum (Minneap Minn) 2014; 20(4 Neuro-ophthalmology): 877-906
Mascialino B, Leinonen M, Meier T. Meta-analysis of the prevalence of Leber hereditary optic neuropathy mtDNA mutations in Europe. Eur J Ophthalmol 2012; 22: 461-465
Newman NJ, Biousse V, Newman SA, et al. Progression of visual field defects in leber hereditary optic neuropathy: experience of the LHON treatment trial. Am J Ophthalmol 2006; 141: 1061-1067
Meyerson C, Van Stavern G, McClelland C. Leber hereditary optic neuropathy: current perspectives. Clin Ophthalmol 2015; 9: 1165-1176
Carelli V, Carbonelli M, de Coo IF, et al. International Consensus Statement on the Clinical and Therapeutic Management of Leber Hereditary Optic Neuropathy. J Neuroophthalmol 2017; 37: 371-381
Skidd PM, Lessell S, Cestari DM. Autosomal dominant hereditary optic neuropathy (ADOA): a review of the genetics and c