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Journals / Turkish Journal of Pediatrics / 2019 / Cilt: 61 - Sayı: 2

Hemophagocytic lymphohistiocytosis associated with oxcarbazepine

Serkan KIRIK
Hatice GÜNEŞ
Sadık YURTTUTAN
Nafiz SARIŞIK
Can ACIPAYAM
Yasemin KIRIK
Pages
297–300
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Bone marrow aspiration may be indicated to confirm thediagnosis when facing a patient with systemic symptoms after newly addedantiepileptic drug treatment.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening multisystem disorder.
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Key Findings & Data:We report the case of a 3-year-old boy with a history of epileptic seizuresin which oxcarbazepine was added to treatment for the last 35 days anddose had been increased.
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Conclusion & Impact:Bone marrow aspiration may be indicated to confirm thediagnosis when facing a patient with systemic symptoms after newly addedantiepileptic drug treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening multisystem disorder. Reports of the disorder as a side effect of drugs are extremelyrare. We report the case of a 3-year-old boy with a history of epileptic seizuresin which oxcarbazepine was added to treatment for the last 35 days anddose had been increased. For 10 days he had a fever, hepatosplenomegaly,rash, edema and other systemic symptoms. He was diagnosed with HLHafter bone marrow examination. Oxcarbazepine treatment was terminatedafter the intravenous immunoglobulin treatment. The next day, clinical andlaboratory results had improved. This is the first HLH report of an associationwith oxcarbazepine. Bone marrow aspiration may be indicated to confirm thediagnosis when facing a patient with systemic symptoms after newly addedantiepileptic drug treatment.

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Cite This Article

KIRIK, S., GÜNEŞ, H., YURTTUTAN, S., SARIŞIK, N., ACIPAYAM, C., KIRIK, Y. (2019). Hemophagocytic lymphohistiocytosis associated with oxcarbazepine. Turkish Journal of Pediatrics, Cilt: 61 - Sayı: 2, 297–300. https://ajindex.com/articles/412065

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References (8)

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