Journals / Turkish Journal of Gastroenterology / 2005 / Cilt: 16 - Sayı: 4

İmmun trombositopenik purpuranın tek bulgu olduğu akut hepatit A olgusu

Immune thrombocytopenic purpura as sole manifestation in a case of acute hepatitis A

Pages
217–219
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Acute hepatitis A should be included in the differential diagnosis of immune thrombocytopenic purpura.

📌 3 Key Takeaways

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Objective & Hypothesis:Acute hepatitis due to hepatitis A virus is usually a benign selflimiting disease during childhood.
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Key Findings & Data:Although many viral infections such as hepatitis B virus, Parvovirus, and Epstein-Barr virus are associated with extrahepatic autoimmune phenomena, such manifestations are rare in patients with acute hepatitis A infection.
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Conclusion & Impact:Acute hepatitis A should be included in the differential diagnosis of immune thrombocytopenic purpura.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hepatit A · Purpura · trombositopenik

Abstract

Acute hepatitis due to hepatitis A virus is usually a benign selflimiting disease during childhood. Although many viral infections such as hepatitis B virus, Parvovirus, and Epstein-Barr virus are associated with extrahepatic autoimmune phenomena, such manifestations are rare in patients with acute hepatitis A infection. Immune thrombocytopenia is a benign, self-limiting disease in children, responding well to treatment and generally associated with viral infections. Immune thrombocytopenic purpura is rarely reported as a manifestation of acute hepatitis A. We report a five-year-old boy with immune thrombocytopenic purpura as the sole manifestation of anicteric acute hepatitis A infection. Acute hepatitis A should be included in the differential diagnosis of immune thrombocytopenic purpura.

Özet

Hepatit A virüsüne bağlı akut hepatit, çocukluk çağında genellikle kendi kendini sınırlayan ve iyileşen bir hastalıktır. Hepatit B virüsü, Parvovirus, Ebstein-Barr virus enfeksiyonları gibi birçok viral enfeksiyon, ekstrahepatik otoimmun fenomenle ilişkili olmasına rağmen, akut hepatit A enfeksiyonlu hastalarda ekstrahepatik otoimmun bulgular nadirdir. İmmun trombositopeni, çocuklarda iyi seyirli, kendini sınırlayan, tedaviye iyi yanıt veren ve genellikle viral enfeksiyonlarla ilişkili bir hastalıktır. İmmun trombositopenik purpura akut hepatit A enfeksiyonu bulgusu olarak nadiren bildirilmiştir. İmmun trombositopenik purpuranın tek bulgu olduğu anikterik akut hepatit A enfeksiyonlu 5 yaşında erkek hasta sunulmuş, akut hepatit A enfeksiyonunun immun trombositopenik purpuranın ayırıcı tanısında yer alması gerektiği düşünülmüştür.

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Cite This Article

TANIR, G., AYDEMİR, C., TUYGUN, N., KAYA, Ö., YARALI, H. N. (2005). İmmun trombositopenik purpuranın tek bulgu olduğu akut hepatit A olgusu. Turkish Journal of Gastroenterology, Cilt: 16 - Sayı: 4, 217–219. https://ajindex.com/articles/411362

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References (12)

  1. Bell BB, Shapiro CG. Hepatitis A virus. In: Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Diseases, 2nd ed. Pennsylvania: Churchill Livingstone Inc; 2003: 1188 – 92
  2. Avci Z, Turul T, Catal F, et al. Thrombocytopenia and emperipolesis in a patient with hepatitis A infection. Pediatr Hematol Oncol 2002; 19: 67-70
  3. Cohen O, Mevorach D, Ackerman Z, et al. Thrombocytopenic purpura as a manifestation of acute hepatitis A. J Clin Gastroenterol 1993; 17: 166-7
  4. Ertem D, Acar Y, Pehlivanoglu E. Autoimmune complications associated with hepatitis A virus infection in children. Ped Infect Dis J 2001; 20: 809-11
  5. Schiff ER. Atypical clinical manifestations of hepatitis A. Vaccine 1992; 10: 18-20
  6. Willner JJ, Uhl MD, Howard SC, et al. Serious hepatitis A: an analysis of patients hospitalized during an urban epidemic in the United States. Ann Intern Med 1998; 128: 111-4
  7. Domenech P, Palomeque A, Martinez-Guitterez A, et al. Severe aplastic anemia following hepatitis A. Acta Hematol 1986; 76: 227-31
  8. Ertem D, Acar Y, Arat C, et al. Thrombotic and thrombocytopenic complications secondary to hepatitis A infection in children. Am J Gastroenterol 1999; 94: 3653-5
  9. Macedo G, Cardoso T, Bernardo L, et al. Purpura: an unusual presentation of HAV infection. J Clin Gastroenterol 1994; 18: 258-9
  10. Ibarra H, Zapata J, Inostroza J, et al. Immune thrombocytopenic purpura associated with hepatitis A. Blut 1986; 52: 371-5
  11. Shenoy R, Nair S, Kamath N. Thrombocytopenia in hepatitis A - an atypical presentation. J Trop Ped 2004; 50: 241-2
  12. Scott JX, Gnananayagam EJ, Gupta S, et al. Thrombocytopenic purpura as initial presentation of acute hepatitis A. Indian J Gastroenterol 2003; 22: 192-3.