Journals / Turkish Journal of Gastroenterology / 2013 / Cilt: 24 - Sayı: 2

Akalazya ile ilişkili erken özofagus kanseri için endoskopik submukozal diseksiyon

Endoscopic submucosal dissection for early esophageal cancer associated with achalasia

Pages
161–166
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is important, therefore, to detect esophageal cancer early.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Esophageal achalasia is often associated with esophageal cancer.
📊
Key Findings & Data:First, esophageal dilatation and dimi- nished peristalsis facilitated the performance of successful endoscopic submucosal dissection.
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Conclusion & Impact:It is important, therefore, to detect esophageal cancer early.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Esophageal achalasia is often associated with esophageal cancer. However, in many cases, esophageal cancer tends to be found in an advanced stage, with a poor prognosis. However, early-stage cancer was detected recently due to the advances in endoscopic ins- truments. In those cases, it is important to facilitate successful treatment by endoscopic submucosal dissection. We analyzed a total of six cases of esophageal cancer with achalasia in four patients treated with endoscopic submucosal dissection. Three features com- mon to all six cases had a bearing on how endoscopic submucosal dissection was performed. First, esophageal dilatation and dimi- nished peristalsis facilitated the performance of successful endoscopic submucosal dissection. Second, the esophageal wall was thic- kened, primarily with muscular tissue. Third, the submucosal layer contained abundant blood vessels that made it difficult to mi- nimize bleeding during dissection. Those findings suggest that endoscopic submucosal dissection for early esophageal cancer asso- ciated with achalasia is a safe and potentially curative procedure. It is important, therefore, to detect esophageal cancer early.

Özet

Özofagus akalazisi, sıklıkla özofagus kanseri ile ilişkilidir. Ancak, birçok hastada özofagus kanseri ileri evrede bulunma eğilimi göstermekte ve prognozu kötü olmaktadır. Öte yandan son yıllarda endoskopik aletlerin gelişmesiyle kanser erken evrede yakalana- bilir olmuştur. Bu hastalarda, başarılı tedaviyi kolaylaştırmak için endoskopik submukozal diseksiyon önemlidir. Özofagus kan- seri ve akalazyası olan 6 hastanın 4 tanesi endoskopik submukozal diseksiyon ile tedavi edildi ve analize alındı. Her altı vaka için 3 ortak nokta endoskopik submukozal diseksiyonun nasıl yapıldığı olmuştur. Birincisi özofagus dilatasyonu ve azalmış peristalsis başarılı endoskopik submukozal diseksiyon performansını artırmıştır. ‹kincisi, özofagus duvarı, primer olarak da kas tabakası ka- lınlaşmıştı. Üçüncüsü, submukozal tabakada diseksiyon sırasında kanamayı en aza indirmeyi zorlaştıran birçok kan damarı ol- masıdır. Bu bulgulara göre, akalazya ile birlikte olan erken özefagus kanseri için endoskopik submukozal diseksiyon güvenilir ve potansiyel olarak küratif bir prosedürdür. Bu nedenle özofagus kanserini erken yakalamak önemlidir.

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Cite This Article

OHKURA, Y., IIZUKA, T., KIKUCHI, D., YAMASHITA, S., NAKAMURA, M., MATSUI, A., MITANI, T., HOTEYA, S., KAISE, M., YAHAGI, N. (2013). Akalazya ile ilişkili erken özofagus kanseri için endoskopik submukozal diseksiyon. Turkish Journal of Gastroenterology, Cilt: 24 - Sayı: 2, 161–166. https://ajindex.com/articles/411341

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