Journals / Turkish Journal of Gastroenterology / 2013 / Cilt: 24 - Sayı: 1

Endosonografik yöntemle peritonun ince iğne aspirasyon biyopsisinin tüberküloz peritonit tanısındaki yeri

Diagnosis of tuberculous peritonitis using endoscopic ultrasound-guided fine-needle aspiration biopsy of the peritoneum

Pages
65–69
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: Endoscopic ultrasound-fine needle aspiration is an efficacious and safe method to obtain tissue from the peritoneum to use in the diagnosis of tuberculous peritonitis.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: Tuberculous peritonitis is prevalent in developing countries and its diagnosis is still challenging due to the lack of specific clinical characteristics and the difficulty in obtaining tissue from the peritoneum without laparoscopy.
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Key Findings & Data:Materials and Methods: Three patients (2 male and 1 female; aged 38, 25, and 65 years, respectively) suspected of having tuberculous peritonitis were recruited into the study.
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Conclusion & Impact:Conclusions: Endoscopic ultrasound-fine needle aspiration is an efficacious and safe method to obtain tissue from the peritoneum to use in the diagnosis of tuberculous peritonitis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aims: Tuberculous peritonitis is prevalent in developing countries and its diagnosis is still challenging due to the lack of specific clinical characteristics and the difficulty in obtaining tissue from the peritoneum without laparoscopy. Endoscopic ultrasound - guided fine needle aspiration is emerging as the most effective and safe method for obtaining tissue from the structures surrounding the gut lumen. Our study aimed to elucidate the efficacy of endoscopic ultrasound-fine needle aspiration of the peritoneum in the diagnosis of tuberculous peritonitis. Materials and Methods: Three patients (2 male and 1 female; aged 38, 25, and 65 years, respectively) suspected of having tuberculous peritonitis were recruited into the study. Clinical evaluation including computed tomography imaging and analysis of ascitic fluid were performed. Endoscopic ultrasound-fine needle aspiration biopsy of the peritoneum was performed trans-gastrically with a 19-gauge ProCore needle in all patients. At least two different areas of the peritoneum suspected to be involved were sampled and paraffin-embedded cell blocks were prepared for each biopsy specimen. Results: Biopsy specimens were positive for Mycobacterium tuberculosis by polimerase chain reaction in 2 patients and positive for multinucleated giant cells in all patients. Treatment for tuberculosis resulted in the resolution of symptoms and ascites. No proce- dure-related complications occured. Conclusions: Endoscopic ultrasound-fine needle aspiration is an efficacious and safe method to obtain tissue from the peritoneum to use in the diagnosis of tuberculous peritonitis.

Özet

Amaç: Tüberküloz peritonit gelişmekte olan ülkelerde sık görülür. Spesifik klinik bulguların olmaması ve laparoskopi kullanmaksızın periton hücre örneklemesinde zorluklar bulunması tanı konusunda klinisyenin zorluk yaşamasına sebep olur. Endoskopik ultrasonografi eşliğinde ince iğne aspirasyonu, barsak lümeni etrafındaki yapıların örneklenmesinde en iyi sonuç alıcı ve en güvenli tanı metodu olarak gündeme gelmektedir. Çalışmamızda, tüberküloz peritonit tanısında peritona yönelik endoskopik ultrasonografi-ince iğne aspirasyonu işleminin etkinliğini araştırmayı hedefledik. Gereç ve Yöntem: Tüberküloz peritonit şüphesi olan 3 hasta (2 erkek, 1 kadın; yaşlar sırasıyla 38, 25 ve 65 idi) çalışmaya alındı. Hastalarda klinik değerlendirme kapsamında yapılan bilgisayarlı tomografik görüntüleme ve asit sıvısı analizleri tanısal değildi. Tüm hastalardan, transgastrik yoldan 19-gauge ProCore iğne ile peritona yönelik endoskopik ultrasonografi-ince iğne aspirasyonu işlemi yapıldı. Periton örneklemesi için en az iki şüpheli infiltre bölgeden örnek alındı. Tüm hastalar için hücre blokları hazırlandı. Bulgular: İki hastadan alınan periton biyopsi örnekleri Mycobacterium tuberculosis polimeraz zincir reaksiyonu incelemesi için pozitifti. Tüm hastaların periton biyopsi örneklerinde multinükleer dev hücreler görüldü. Tüberküloz tedavisi ile tüm hastalarda semptomlar iyileşti ve asit kayboldu. İşleme yönelik herhangi bir komplikasyon yalanmadı. Sonuç: Endoskopik ultrasonografi-ince iğne aspirasyon yöntemi, tüberküloz peritonit tanısında periton örneklemesi için etkili ve güvenli bir tanısal metod olarak kullanılabilir.

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Cite This Article

KOCAMAN, O., DANALIOĞLU, A., İNCE, A. T., TOZLU, M., ŞENTÜRK, H. (2013). Endosonografik yöntemle peritonun ince iğne aspirasyon biyopsisinin tüberküloz peritonit tanısındaki yeri. Turkish Journal of Gastroenterology, Cilt: 24 - Sayı: 1, 65–69. https://ajindex.com/articles/411336

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