HLA tissue status in patients with gluten sensitive enteropathy

Key Findings & Data:Fifty five healthy kidney donors were enlisted as controls.HLA B8, B12, DQ2 and DQ3 were significant (p<0.05) but, DR3 was far more significant (p< 0.005).

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Conclusion & Impact:This relative risk for DR3 / DR7 was 11, DR3 / DR3 was 6.6 and DR5 I/ DR7 was 0.89

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

We studied HLA tissue status in 16 fully diagnosed gluten enteropathy patients. Fifty five healthy kidney donors were enlisted as controls.HLA B8, B12, DQ2 and DQ3 were significant (p<0.05) but, DR3 was far more significant (p< 0.005). This relative risk for DR3 / DR7 was 11, DR3 / DR3 was 6.6 and DR5 I/ DR7 was 0.89

Özet

Bu çalışmada tanısı kesinleşmiş 16 gluten enteropatili hastada HLA klas I ve II grupları araştırılmıştır. Kontrol grubu olarak 55 sağlıklı böbrek vericisinin doku grupları alınmıştır. İstatistiksel olarak HLA B8, B13, DQ2 ve DQ3 varlığı anlamlı (p< 0.05), DR 3 varlığı ise ileri derecede anlamlı (p< 0.005) olarak bulunmuştur. DR fenotiplerine göre rölatif risk DR3/ DR 7 için 11, DR3 /DR 3 için 6.6 ve DR5 / DR7 için 0.89 bulunmuştur.

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Cite This Article

TEZEL, A., ÜLKER, A., ENSARİ, A., BAYSAL, Ç., DALVA, K., DAĞLI, Ü., SERİN, A., ÖVER, H., ALKIM, C. (1998). HLA tissue status in patients with gluten sensitive enteropathy. Turkish Journal of Gastroenterology, Cilt: 9 - Sayı: 3, 269–271. https://ajindex.com/articles/411281