Journals / Turkish Journal of Gastroenterology / 1999 / Cilt: 10 - Sayı: 1

Kolitis ülserozalı olgularda p-ANCA varlığının klinik ve laboratuvar parametrelerle ilişkisi

The relationship of the clinical and laboratory parameters with the presence of p-ANCA in cases with ulcerative colitis

Pages
60–65
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although this may be explained by the more intensive corticosteroid treatment given to these patients, there is a need for furter research on this subject with a larger number of pancolitis patients.

📌 3 Key Takeaways

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Objective & Hypothesis:In this study , the relationship of clinical and laboratory results with ANCA positivity in patients with ulcerative colitis determined by indirect immunofloressein method was investigated (total ANCA is 47.8 % ; 41.3 % p-ANCA, 6.5% c-ANCA).
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Key Findings & Data:The activitiy level of the disease, duration of disease, affected region of the colon, kind of therapy gıven, use of steroids, age, sex, erythrocyle sedimentation rate (ESR), hematocrit level, and serum albumin level were not found to affect ANCA positivity (for each of them p>0.05).
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Conclusion & Impact:Although this may be explained by the more intensive corticosteroid treatment given to these patients, there is a need for furter research on this subject with a larger number of pancolitis patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kolit · ülseratif · Ultrasonografi

Abstract

In this study , the relationship of clinical and laboratory results with ANCA positivity in patients with ulcerative colitis determined by indirect immunofloressein method was investigated (total ANCA is 47.8 % ; 41.3 % p-ANCA, 6.5% c-ANCA). The activitiy level of the disease, duration of disease, affected region of the colon, kind of therapy gıven, use of steroids, age, sex, erythrocyle sedimentation rate (ESR), hematocrit level, and serum albumin level were not found to affect ANCA positivity (for each of them p>0.05). Interestingly, four patients with pancolitis were all found to be p-ANCA negative. Although this may be explained by the more intensive corticosteroid treatment given to these patients, there is a need for furter research on this subject with a larger number of pancolitis patients.

Özet

Bu çalışmada kolitis ülserozada indirekt immünflöresan yöntemle saptamış olduğumuz ANCA pozitifliği ile (% 47.8: % 41.3 p-ANCA, % 6.5 c-ANCA) bazı klinik ve laboratuvar değerlerin ilişkili olup olmadığı araştırıldı. ANCA pozitifliği üzerine hastalığın aktivasyon durumu, hastalık süresi, kolonun etkilenmiş olduğu bölge, almakta olduğu tedavi, steroid alıp almama durumu, yaş, cinsiyet, eritrosit sedimantasyon hızı, hematokrit, serum albumin düzeyleri etkili bulunmadı (bütün değerlendirmelerde p> 0.05). İlginç olarak pankolitli 4 olgumuzun hiçbirinde p-ANCA pozitifliğine rastlanmadı. Bu durum bu hastalara daha yoğun kotikosteroid tedavisi uygulanmasının bir sonucu olabilir. Ancak bu konuda pankolitli olgu sayısının fazla olduğu başka çalışmalara ihtiyaç vardır.

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Cite This Article

KAYATAŞ, M., DÖKMECİ, A., PARLAK, E. (1999). Kolitis ülserozalı olgularda p-ANCA varlığının klinik ve laboratuvar parametrelerle ilişkisi. Turkish Journal of Gastroenterology, Cilt: 10 - Sayı: 1, 60–65. https://ajindex.com/articles/411254

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