AI Summary & Key Takeaways
AI InsightWe report a rare case of nodular regarative hyperplasia of the liver, with onset of symptom in childhood.
📌 3 Key Takeaways
Abstract
Nodular regenerative hyperplasia of the liver is characterized by hepatocellular nodules distributed throughout the liver in the absence of fibrous septa between the nodules. In the literature, most reports have been single cases so that the prevalence and clinical significance of the disease is not exactly known. The critical lesion is obliterative portal venopathy which is obstruction to terminal radicals of hepatic arterioles and portal venules, possibly secondary to endothelial cell damage. Resultant hepatic ischemia may be responsible for induction of the nodular regenerative change. Portal hypertension which is secondary to nodular regenerative hyperplasia and is often complicated by bleeding esophageal varices. We report a rare case of nodular regarative hyperplasia of the liver, with onset of symptom in childhood.
Özet
Nodüler rejeneretif hiperplazi, aralarında fibroz septa olmaksızın yaygın hepatosüllüler nodülerin varlığı ile karakterizedir. Çoğu çalışma olgu sunumundan ibaret olduğundan sıklık ve klinik önemi iyi bilinmez. Kritik lezyon, endotel hasarına bağlı terminal hepatik arterial ve portal venüllerin obliteratif vaskülopatisidir. Ortaya çıkan istemi, nodüler değişikliğe yol açar. Nodüler hiperplaziye sekunder portal hipertansiyon, özofagus varis kanaması nedenidir. Bu çalışmada, çocukluk çağında başlayan bir nodüler reganeratif hiperplazi olgusu sunuyoruz.