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Journals / Turkish Journal of Gastroenterology / 2003 / Cilt: 14 - Sayı: 4

Duodenogastric reflünün Helicobacter pylori varlığı ve gastrik histopatolojik değişikliklere etkileri

The effect of duodenogastric reflux on Helicobacter pylori presence and gastric histopathologic changes

Vildan TAŞKIN
Murat SEDELE
Osman SAKA
BÜLENT KANTARÇEKEN
Pages
239–242
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Duodenogastric reflux does not affect the pr esence of Helicobacter pylori and gastric histopathologic changes.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aims: In this study, we investigated the presence of Helicobacter pylori infection and gastric histological changes in unoperated patients with and without duodenogastric reflux.
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Key Findings & Data:Methods: Twenty-two women and 15 men, mean age of 51.17 years, who had duodenogastric reflux during endoscopy were included.
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Conclusion & Impact:Conclusion: Duodenogastric reflux does not affect the pr esence of Helicobacter pylori and gastric histopathologic changes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Duodenogastrik reflü · Gastrit · Endoskopi

Abstract

Background/aims: In this study, we investigated the presence of Helicobacter pylori infection and gastric histological changes in unoperated patients with and without duodenogastric reflux. Methods: Twenty-two women and 15 men, mean age of 51.17 years, who had duodenogastric reflux during endoscopy were included. Thirty-seven age-and gender-matched patients without duodenogastric reflux served as controls. The Helicobacter pylori infection was detected by histology. The Helicobacter pylori density and gastric histology according to the modified Sydney system were evaluated with specimens from antrum, corpus and fundus. Results: The presence of Helicobacter pylori, Helicobacter pylori density, chronic inflammation score, lymphoid follicles, atrophy, and intestinal metaplasia were similar in patients with and without duodenogastric reflux (p>0.05). Acute inflammation was found to be lower in the antrum (p<0.05) in the duodenogastric reflux-positive group. Conclusion: Duodenogastric reflux does not affect the pr esence of Helicobacter pylori and gastric histopathologic changes.

Özet

Amaç: Bu çalışmada duodenogastrik reflünün Helicobacter pylori varlığı ve gastrik histopatolojik değişikler üzerine etkileri araştırıldı. Yöntem: Endoskopide duodenogastrik reflü saptanan 22'sı kadın ve 15'i erkek, yaş ortalaması 51.17 yıl olan 37 olgunun sonuçları, endoskopide duodenogastrik reflü saptanmayan yaş ve cins özellikleri benzer olan 37 olgunun sonuçları ile karşılaştırıldı. Helicobacter pylori varlığı histolojik olarak saptandı. Antrum, korpus ve fundustan alınan biopsilerde Helicobacter pylori yoğunluğu ve gastrik histopatolojik değişiklikler modifiye Sydney sistemi ile değerlendirildi. Bulgular: Duodenogastrik reflülü olgularda antrumda akut inflamasyon skoru istatiksel açıdan anlamlı bir farklılık gösterirken Helicobacter pylori varlığı, Helicobacter pylori yoğunluğu, kronik inflamasyon skoru, lenfoid follikul, atrofi, intestinal metaplazi varlığı açısından her iki grup arasında farklılık saptanmadı. Sonuç: Duodenogastrik reflü Helicobacter pylori varlığı ve gastrik histopatolojik değişiklikleri etkilememektedir.

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Cite This Article

TAŞKIN, V., SEDELE, M., SAKA, O., KANTARÇEKEN, B. (2003). Duodenogastric reflünün Helicobacter pylori varlığı ve gastrik histopatolojik değişikliklere etkileri. Turkish Journal of Gastroenterology, Cilt: 14 - Sayı: 4, 239–242. https://ajindex.com/articles/411208

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