Journals / Turkish Journal of Gastroenterology / 2011 / Cilt: 22 - Sayı: 1

Migren başağrısı olan ve sağlıklı çocuklarda çölyak hastalığı sıklığının karşılaştırılması

A comparative study of celiac disease in children with migraine headache and a normal control group

Pages
32–35
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore, diagnostic tests for celiac disease are not necessary as a part of the management of migraine headache.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: Migraine headache is one of the most frequent types of headache in children in which multiple factors, including environmental and genetic, are involved.
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Key Findings & Data:Methods: A total of 100 patients with migraine headache according to the International Headache Society criteria were enrolled in the study. 1500 children without history of headache or other medical diseases participating in another study for detection of the prevalence of celiac disease were selected in this study as a control group.
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Conclusion & Impact:Therefore, diagnostic tests for celiac disease are not necessary as a part of the management of migraine headache.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aims: Migraine headache is one of the most frequent types of headache in children in which multiple factors, including environmental and genetic, are involved. Celiac disease is an autoimmune-mediated disease with intolerance to gluten. The clinical spectrum of celiac disease is wide. Patients may present with malabsorption symptoms or extra-intestinal involvement, or can be totally asymptomatic. The association of migraine headache and celiac disease is not well known. The aim of this study was to assess the prevalence of celiac disease in children with migraine headache, in order to detect any relationship between them. Methods: A total of 100 patients with migraine headache according to the International Headache Society criteria were enrolled in the study. 1500 children without history of headache or other medical diseases participating in another study for detection of the prevalence of celiac disease were selected in this study as a control group. Serum total IgA and anti-tissue transglutaminase IgA (anti- tTGA) antibodies were measured. In cases with positive serologic tests, duodenal biopsy was performed for confirmation of celiac disease. Results: Two of 100 patients (2%) were found to have positive serologic tests for celiac disease, compared with 30 of 1500 children (2%) in the control group who had celiac disease. Conclusions: The results of this study showed that the prevalence of celiac disease was not higher in patients with migraine compared with the control group. Therefore, diagnostic tests for celiac disease are not necessary as a part of the management of migraine headache.

Özet

Amaç: Migren başağrısı; patogenezinde birçok çevresel ve genetik faktörün sorumlu olduğu, çocuklarda görülen başağrısı tipleri arasında en sık karşılaşılanıdır. Çölyak hastalığı glutene intolerans ile karakterize immun sistem aracılığı ile ortaya çıkan bir tablodur. Çölyak hastalığının klinik spektrumu geniştir. Hastalar, malabsorbsiyon veya ekstraintestinal tutulum ile prezente olabilirler veya tamamiyle asemptomatik olabilirler. Migren tipi baş ağrısı ile çölyak hastalığı arasındaki ilişki iyi bilinmemektedir. Bu çalışmanın amacı migren tipi baş ağrısı olan çocuklarda çölyak hastalığı prevalansının ortaya konulması ve aralarındaki ilişkinin tespit edilmesidir. Yöntem: Uluslararası Başağrısı Derneği kriterlerine göre migren başağrısı olan toplam 100 hasta çalışmaya dahil edildi. Çölyak hastalığının çocuklardaki sıklığının tespit edilmesi amacı ile başka bir araştırmaya katılmış olan başağrısı veya başka sağlık sorunu olmayan 1500 çocuk kontrol grubu olarak seçildi. Serum toplam IgA ve doku transglutaminaz IgA (Anti-tTGA) antikorları düzeyleri ölçüldü. Bulgular: Yüz hastanın ikisinde (%2) çölyak hastalığı için serolojik olarak pozitif bulundu, buna karşılık 1500 kontrolün 30’unda (%2) çölyak hastalığı bulunmaktaydı. Sonuç: Bu çalışmanın sonucu göstermiştir ki, migren hastalarında çölyak hastalığı hastalığı sıklığı kontrol grubuna göre artmış değildir. Bu durumda migren başağrısının değerlendirilmesinde çölyak hastalığı için tanısal testlerin gerçekleştirilmesine gerek yoktur.

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Cite This Article

INALOO, S., DEHGHANI, S. M., FARZADI, F., HAGHIGHAT, M., IMANIEH, M. H. (2011). Migren başağrısı olan ve sağlıklı çocuklarda çölyak hastalığı sıklığının karşılaştırılması. Turkish Journal of Gastroenterology, Cilt: 22 - Sayı: 1, 32–35. https://ajindex.com/articles/411123

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