Journals / Turkish Journal of Gastroenterology / 2018 / Cilt: 29 - Sayı: 6

Results of 1001 liver transplantations in 23 years: Ege University experience

Pages
664–668
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Ege University is one of the biggest liver transplant centers inTurkey for both technical and educational perspective.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/Aims: Liver transplantation (LT) is now the standard of care for most end-stage liver diseases.
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Key Findings & Data:Over the next 30 years, advances in medicine and technology will greatly improve the survival rates of patients after this procedure.
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Conclusion & Impact:Ege University is one of the biggest liver transplant centers inTurkey for both technical and educational perspective.
🔬Design:Modeling & Simulation
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Özet

Background/Aims: Liver transplantation (LT) is now the standard of care for most end-stage liver diseases. Over the next 30 years, advances in medicine and technology will greatly improve the survival rates of patients after this procedure. The aim of the present studywas to analyze retrospectively the results of 1001 patients withLT.Materials and Methods: Medical reports of 989 patients were analyzed retrospectively. Data were obtained from the patient’s datachart. Descriptive statistics were used to describe continuous variables (mean, median, and standard deviation).Results: A total of 1001 LTs for 989 recipients were performed at Ege University Organ Transplantation and Research Center between1994 and 2017. Therewere 639 male and 350 female recipients. Among 1001 LTs, there were 438 deceased donors and 563 living donors. The age interval of the patients was 4 months to 71 years old. The median Model for End-Stage Liver Disease score was 20. Therewere 12 deceased liver donors using the split method. There were 12 cases subject to retransplantation. In living donor LT grafts, 423right lobes, 46 left lobes, and 94 left lateral sectors were used. In the first monitoring,the total annual mortality rate was 130 cases (13%).The mortality rate in retransplantation was found to be 66%. A 1-year survival rate of 87% was generally established.Conclusion: LThas been improving consistently over the last two decades. Ege University is one of the biggest liver transplant centers inTurkey for both technical and educational perspective.

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Cite This Article

ZEYTUNLU, M., UĞUZ, A., ÜNALP, Ö., ERGÜN, M. O., karasu, Z., GÜNŞAR, F., AKARCA, U. S., BARBET, F. Y., TURAN, İ., NART, D., TEKİN, F., ÖZÜTEMİZ, Ö., ULUKAYA, S., DENİZ, N., AYDOĞDU, S., ÖZGENÇ, F., TASÇI, E., SERTÖZ, Ş. R., PARILDAR, M., ELMAS, N., HARMAN, M., EZG, E. (2018). Results of 1001 liver transplantations in 23 years: Ege University experience. Turkish Journal of Gastroenterology, Cilt: 29 - Sayı: 6, 664–668. https://ajindex.com/articles/411053

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References (4)

  1. Moore FD, Wheele HB, Demissianos HV, et al. Experimental whole-organ transplantation of the liver and of the spleen. Ann Surg 1960; 152: 374-87. [CrossRef] Starzl TE, MarchioroTL,Vonkaulla KN, Hermann G, Brittain RS, Waddell WR. Homotransplantation of the Liver in Humans. Surg Gynecol Obstet 1963; 117: 659-76.
  2. Starzl TE, Groth CG, Brettschneider L, et al. Orthotopic homotransplantations of the human liver. Ann Surg 1968; 168; 392-415. [CrossRef] Calne RY, White DJ. The use of cyclosporine A in clinical organ grafting. Ann Surg 1982; 196: 330-7. [CrossRef] Iwatsuki S, Starzl TE, Todo S, et al. Experience in 1000 liver transplants under cyclosporine-steroid therapy;a survival report. Transplant Proc 1989; 20: 498-504.
  3. Todo S, Fung JJ, Demetris AJ, Jain A, Venkataramanan R, Starzl TE. Early trials with FK 506 as primary treatment in liver transplantation. Transplant Proc 1990; 22: 13-6. Broelsch CE,Emond JC,Whitington PF, Thislethwaite JR, Baker AL, Lichtor JL. Application of reduced-size liver transplants as split grafts, auxiliary orthotopic grafts, and living related segmental transplants. Ann Surg 1990; 212: 368-75. [CrossRef] Bismuth H, Houssin D. Reduced-sized orthotopic liver graft in hepatic transplantation in children. Surgery 1984; 95; 367-70.
  4. Pichlmayr R, Ringe B, Gubernatis G, HaussJ, Bunzendahl H. Transplantation of a donor liver to 2 recipients (splitting transplantation)- a new method in the further development of segmental liver transplantation. Langenbecks Arch Chir 1988; 373: 127-30. [CrossRef] Strong RW, Lynch SV, Ong TH, et al. Successful liver transplantation from a living donor to her son. N Engl J Med 1990; 322: 1505-7. [CrossRef] Yamaoka Y, Washida M, Honda K, et al. Liver transplantation using a right lobe graft from a living donor. Transplantation 1994; 57: 1127-30. [CrossRef] Hashikura Y, Makuuchi M, Kawasaki S, et al. Successful living related partial liver transplantation to an adult patient. Lancet 1994; 343: 1233-4. [CrossRef] Lo CM, Fan ST, Liu CL, et al. Extending the limit on the size of adult recipient in living donor liver transplantation using extended right lobe graft. Transplantation 1997; 63: 1524-8. [CrossRef] Cherqui D, Soubrane O, Husson E, et al. Laparoscopic living donor hepatectomy for liver transplantation in children. Lancet 2002; 359: 392-6. [CrossRef] Moray G, Arslan G, Haberal M. The history of liver transplantation in Turkey. Exp Clin Transplant 2014; 12: 20-3. [CrossRef] Tokat Y, Yuzer Y, Karasu Z, et al. N