AI Summary & Key Takeaways
AI InsightAs a result, it was seen that vitamin E reduced lipid peroxidation, and thus preventing mucosal damage.
📌 3 Key Takeaways
Abstract
In this experimental study, free oxygen radi¬cals resporisible for various tissue damages and the ef¬fects of vitamin E, used to eliminate these radicals, were investigated. A total of 34 rats was divided into four groups (control group, stress-induced group, stress+ethanol-induced group and stres+ethanol+vita-min E induced group), and levels of malondialdehyde (MDA), which is a metabolite of free oxygen radicals in stomach tissues, were measured. MDA levels were found to be higher in stress and stress+ethanol groups in respect with control group(p<0.01). MDA levels in vi¬tamin E induced stres+etanol group were found close to those in control group (p>0.05). As a result, it was seen that vitamin E reduced lipid peroxidation, and thus preventing mucosal damage.
Özet
Çeşitli doku hasarından sorumlu olan serbest ok¬sijen radikalleri ve bu radikallerin elimine edilmesinde kullanılan antioksidan maddelerden E vitamininin et¬kileri bu deneysel çalışmada incelenmiştir. Toplam 34 sıçdn 4 gruba ayrılarak (kontrol grubu, stres grubu, stres+Etanol grubu ve stres+Etanol+E vitamini grubu) mide dokularında serbest oksijen radikallerinin bir me-taboliti olan Malondialdehit (MDA) düzeyleri "thiobar-bitürik asit metodu" ile ölçüldü. MDA düzeyleri stres ve stres+etanol gruplarında kontrol grubuna göre yüksek bulundu(p 0.05). Sonuç olarak E vitamini lipid perok-sidasyonunu azalttığı, dolayısı ile mokozal tahribata engel olduğu görüldü.