Journals / Turkish Journal of Gastroenterology / 1997 / Cilt: 8 - Sayı: 2

İnflamatuvar barsak hastalıklı hastalarda otonom sinir fonksiyon bozukluğu

Autonomic nerve dysfunction in patients with inflammatory bowel disease

Pages
210–213
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclu¬sion; these results suggest AN can be accepted as an ex¬tensive extra intestinal manifestation of inflammatory bowel diseases (IBD) especially in CD.

📌 3 Key Takeaways

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Objective & Hypothesis:Autonomic neuropathy (AN) was evaluated in 11 patients with Crohn's disease (CD), 48 patients with ulcerative colitis (UC) and 20 healthy subjects (me¬an age 35 years, range 17-19 years) by non invasive car¬diac autonomic reflex tests.
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Key Findings & Data:Mean age of CD patients was 30 (range 22-55) and mean age of UC patients was 35 (range 19-68).
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Conclusion & Impact:In conclu¬sion; these results suggest AN can be accepted as an ex¬tensive extra intestinal manifestation of inflammatory bowel diseases (IBD) especially in CD.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Autonomic neuropathy (AN) was evaluated in 11 patients with Crohn's disease (CD), 48 patients with ulcerative colitis (UC) and 20 healthy subjects (me¬an age 35 years, range 17-19 years) by non invasive car¬diac autonomic reflex tests. Mean age of CD patients was 30 (range 22-55) and mean age of UC patients was 35 (range 19-68). Relation of presence of AN with age, disease duration, disease activity and extent of illnesses are assessed. Autonomic dysfunction was present in 63.7% of CD and 29.3% of UC while none in healthy control group, (p<0.001). No relationship has been found between AN O.nd the patients age, duration of sickness, localization and activity. UC cases had mainly vagal AN, while CD cases had mainly sympathetic. In conclu¬sion; these results suggest AN can be accepted as an ex¬tensive extra intestinal manifestation of inflammatory bowel diseases (IBD) especially in CD.

Özet

Otonom nöropati (ON) Crohn hastalıklı (CH) 11, ülseratif kolitli (ÜK) 48 hastada ve 20 sağlıklı kontrol¬de non-invaziv kardiak otonom refleks testlerle araştı¬rılmıştır. CH'nın ortalama yaşı 30 (22-55 arasında), ÜK'li olguların ise 35 (19-68) dir. ON varlığı ile yaş, hastalık süresi, hastalık aktivitesi ve lokalizasyon ara¬sındaki ilişki araştırılmıştır. ON, CH'lı olguların %63.7'sinde, ÜK'li olguların %29.3'ünde izlenirken, sağlıklı kontrol olgularının hiçbirisinde saptanmamış¬tır. Gruplar arasındaki fark istatistiki olarak anlamlı bulunmuştur (p<0.001). ON ile hastanın yaşı, hastalık süresi, aktivitesi ve lokalizasyonu arasında anlamlı bir ilişki bulunamamıştır. ÜK'li olgularda vagal nöropati, CH'lı olgularda sempatik nöropati izlenmiştir. Sonuç olarak; ON inflamatuvar barsak hastalığının özellikle de CH'nın yaygın görülen barsak dışı komplikasyonu olarak kabul edilebilir..

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Cite This Article

DAĞLI, Ü., ÖVER, H., ÜLKER, A., TEZEL, A., ONARAN, L. (1997). İnflamatuvar barsak hastalıklı hastalarda otonom sinir fonksiyon bozukluğu. Turkish Journal of Gastroenterology, Cilt: 8 - Sayı: 2, 210–213. https://ajindex.com/articles/411003