Prevalance of hepatitis B and hepatitis C infection in leprosy patients

Whilst anti-HBs and HBsAg positivity levels were concurrent with available data, anti-HCV seropositivity at 15.2% was found to be higher than current data in the literature

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study was to investigate the prevalance of hepatitis-B and hepatitis-C infection in leprosy patients.

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Key Findings & Data:Fourty-six patients comprising 15 (32.6%) women and 31 (67.3%) men with an age range of 20-75 years (mean of 53.8 years) were investigated.

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Conclusion & Impact:Whilst anti-HBs and HBsAg positivity levels were concurrent with available data, anti-HCV seropositivity at 15.2% was found to be higher than current data in the literature

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Hepatit B virüsü · Hepatit C virüsleri · Hepatit C antikorları

Abstract

The aim of this study was to investigate the prevalance of hepatitis-B and hepatitis-C infection in leprosy patients. Fourty-six patients comprising 15 (32.6%) women and 31 (67.3%) men with an age range of 20-75 years (mean of 53.8 years) were investigated. The average period of disease was 33.5±11.2 years. Hepatitis-B markers and anti-HCV antibodies were tested by Elisa method. We found anti-HCV positivity in 15.2%, HBsAg positivity in 10.8% and anti-Hbs positivity in 50% of patients. The 15.2% seropositivity of anti-HCV found in Leprosy patients was higher and seropositivities of anti-HBS and HBsAg, 50% and 10.8% were in accordance with the data in the literature. Whilst anti-HBs and HBsAg positivity levels were concurrent with available data, anti-HCV seropositivity at 15.2% was found to be higher than current data in the literature

Özet

Bu çalışmada Lepralı hastalarda hepatit-B virusu ve hepatit-C virusu infeksiyon sıklığını araştırmayı amaçladık. Çalışmaya 46 hasta (15 kadın, 31 erkek) alındı. Hastaların yaş aralığı 20-75, yaş ortalaması 53.8 yıl, ortalama hastalık süreleri 33.5±11.2 yıldı. Hepatit-B markerları ve anti-HCV Elisa yöntemi ile araştırıldı. Anti-HCV pozitifliği %15.2, HBsAg pozitifliği %10.8 ve anti-HBs pozitifliği ise %50 olarak bulundu. Sonuçta anti-HCV pozitifliği literatürde bildirilen oranlardan yüksek, HBsAg ve anti-HBs pozitifliği ise benzer bulundu.

Keywords

Hepatit B virüsü Hepatit C virüsleri Hepatit C antikorları Hepatit B antikorları Yaygınlık Lepra Hepatitis B virus Hepatitis C-Like Viruses Hepatitis C Antibodies Hepatitis B Antibodies Prevalence Leprosy

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Cite This Article

ALTIPARMAK, E., KOÇAK, M., KUNDAKÇI, N., KOŞAR, Y., PENÇE, B., ŞAHİN, B., TEMUÇİN, G. (1999). Prevalance of hepatitis B and hepatitis C infection in leprosy patients. Turkish Journal of Gastroenterology, Cilt: 10 - Sayı: 3, 253–255. https://ajindex.com/articles/410995

References (14)

Ridley DS,Jopling WH. Classification of leprosy according to immunity.A Five group system. Int J Leprosy 1966: 34-255
Frommel D, Tekle-Hasimanot R, Berhe N et al. A survey of anti-bodies to Hepatitis C virus in Ethiopia. Am J Trop Med Hyg 1993; 49: 435-9
Denis F, Aussel L, Ranger S. et al. Prevalence of antibodies to hepatitis C virus among patients with leprosy in several African Countries and the Yemen. J Med Virol 1994; 43: 1-4
Tanaka M, Nishino H, Gaku K et al. Survey of antibody to HCV in national leprosarium Suruga. Nippon Rai Gakkai Zasshi 1992; 61: 88-91
Sakarya S. Ülkemizde çeşitli risk gruplarında C hepatit sıklığı GATA-Haydarpaşa, Uzmanlık Tezi, İstanbul 1993
Balık İ, Onul M, Kandilci S et al. Çeşitli gruplarda HCV antikorları prevelansı. Turk J Gastroenterohepatology 1990;1:55
Doğanay M, Patıroğlu T, Utağ C et al. Değişik gruplarda HbsAg, Anti-HCV ve Anti-HDV pozitifliğinin karşılaştırılması. Mikrobiyol Bült 1993; 27: 107
Yenice N, Çolakoğlu E, Gül K et al. Diyarbakır'da kan donörlerinde Hepatit-C virus antikoru prevelansı. Turk J Gastroenterol 1993; 4: 41-2
Durman R, Tecimer C, Durmaz B et al. Anti-HCV positivity among diffrent risk groups in Malatya-Turkey. Infeksiyon Dergisi 1992; 6: 257
Rosa H, Costa AP, Ferraz ML et al. Association between leprosy and hepatitis B infection.A survey in Goiania, Central Brasil Rev Inst Med Trop 1992; 34: 421-6
Öneş S, Saylan T,Yalçın İ et al. Lepralı hastalarda HbsAg, HbsAb ve alfafetoprotein I.Ulusal Lepra Semineri Kitabı, İstanbul 1980;138
Kundakçı N, Taşpınar A, Erdem C et al. Değişik klinik spektrumdaki lepra hastalarında HBV enfeksiyonu serolojik işaretleri Lepra Mecmuası 1989;197:20
Değertekin H, Canoruç F, Göral V et al. Diyarbakır ve çevresinde sağlıklı kişilerde HbsAb taraması. VI. Türk Gastroenteroloji Kongresi 22-25 Ekim 1995; Kogre Kitabı 1986; 336
Yılmaz M, Kılıç SS, Aslan IN et al. Elazığ Belediyesi temizlik işçileri ve EBK işçilerinde HbsAg araştırması.infeksi-yon Dergisi 1990.