SavedAdd your journal

Journals / Turkish Journal of Gastroenterology / 1999 / Cilt: 10 - Sayı: 1

Hepatotoksisitenin olası bir nedeni: Karboksimetil sellüloz

A possible cause of hepatotoxicity: Carboxymethyl cellulose

Buket ALTUNTAŞ
Özlem YILMAZ
Pages
72–73
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Following detailed evalution of the patients history, it was found that a mucoadhesive material (Gantrez) had been used on her false palate during.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A four month old girl presented with persistently elevated liver enzymes for which no cause was found in spite of multiple investigations.
📊
Key Findings & Data:Following detailed evalution of the patients history, it was found that a mucoadhesive material (Gantrez) had been used on her false palate during.
💡
Conclusion & Impact:Liver enzymes returned to normal limits within five days of discontinving adhesive application.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Karboksimetilselüloz · Karaciğer · Carboxymethylcellulose

Abstract

A four month old girl presented with persistently elevated liver enzymes for which no cause was found in spite of multiple investigations. Following detailed evalution of the patients history, it was found that a mucoadhesive material (Gantrez) had been used on her false palate during. The previous three months. Liver enzymes returned to normal limits within five days of discontinving adhesive application.

Özet

4 aylık kız hasta, karaciğer fonksiyon testlerinde yükseklik nedeni ile polikliniğimize başvurdu. Etyolojiye yönelik yapılan araştırmalarla enzim yüksekliğini açıklayacak bir neden bulunamadı. Ayrıntılı bir öykü ile, yarık damağı olan hastanın, son 3 aydır, protez damak yapıştırıcısı olarak mukoadheziv bir materyal (Gantrez) kullandığı öğrenildi. İlacın kullanımının kesilmesinden 5 gün sonra, karaciğer enzimleri normale döndü.

🔖

Cite This Article

ALTUNTAŞ, B., YILMAZ, Ö. (1999). Hepatotoksisitenin olası bir nedeni: Karboksimetil sellüloz. Turkish Journal of Gastroenterology, Cilt: 10 - Sayı: 1, 72–73. https://ajindex.com/articles/410973

References (1)

  1. Roberts EA, Spilberg SP. Drug-induced hepatotoxicity in children. In Walker WA, Durie PR, 2) Hamilton JR, Walker-Smith JA, Watkins JB, Editors: Pediatric Gastrointestinal Disease, 2nd, Philadelphia, B.C.Decker Inc, 1996; 1083-101. 3) Maddrey WC, Zimmerman HJ. Toxic and drug induced hepatitis.In Schiff L, Schiff ER, editors: Diseases of the liver, 6th, Philadelphia, JB Linpincott, 1987; 591-667. 4) Sherlock S, Dooley J. Drugs and the Liver. In Sherlock S, Dooley J Editors: Diseases of the liver and biliary system, 9th, London, Blackwell Scientific Publications, 1993; 322-56. 5) Klugman FB. Enhancement of paracetamol induced hepatotoxicity by prior treatment with carboxymethylcellulose. Pharmacol Res Common 1984; 16: 313-8. 6) Decorti G. Enhancement of adriamycin toxicity by carboxymethylcellulose in mice. Toxical Appl Pharmacol 1983; 71: 288-93.