Journals / Turkish Journal of Gastroenterology / 2003 / Cilt: 14 - Sayı: 2

Prolaps gastropati üst gastrointestinal sistem kanama nedeni midir?

Is prolapse gastropathy a cause of upper gastrointestinal bleeding?

Pages
106–110
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: According to the results of this study, prolapse gastropathy is not a cause of hematemesis.

📌 3 Key Takeaways

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Objective & Hypothesis:Prolapse gastropathy is a clinical syndrome involving the invagination of a part of the gastric mucosa into the lower esophagus resulting in well demarcated hemorrhagic mucosa and sometimes bleeding.
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Key Findings & Data:Methods: The study groups comprised of 941 patients with hematemesis and 54 with recurrent retching and vomiting.
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Conclusion & Impact:Conclusions: According to the results of this study, prolapse gastropathy is not a cause of hematemesis.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Prolaps · Mide mukozası · Gastrointestinal kanama

Abstract

Prolapse gastropathy is a clinical syndrome involving the invagination of a part of the gastric mucosa into the lower esophagus resulting in well demarcated hemorrhagic mucosa and sometimes bleeding. The importance of this syndrome is that it has been reported as a cause of hematemesis. As this syndrome is considered to be seen in patients with retching and vomiting and to be one of the causes of upper gastrointestinal bleeding, this study was undertaken to evaluate its frequency and importance in our patients. Methods: The study groups comprised of 941 patients with hematemesis and 54 with recurrent retching and vomiting. Biopsies were obtained from the prolapsing mucosa when detected. Hematoxylin and eosin stained specimens were reviewed by an experienced histopathologist. Results: Prolapse gastropathy was detected in 20 patients (2%), of whom six (0.6%) were in the hematemesis group and 14 (25.9%) in the retching and vomiting group. The location of the lesion was the greater curvature in 10 patients (50%), lesser curvature in seven patients (35%) and anterior wall in three patients (15%). In all six cases from the hematemesis group, bleeding was not related to prolapse gastropathy because other causative lesions were identified. Histologie evaluation of the biopsies revealed acute inflammation, chronic inflammation and submucosal hemorrhage. Conclusions: According to the results of this study, prolapse gastropathy is not a cause of hematemesis. Other causes should be identified when prolapse gastropathy is detected in a patient with hematemesis.

Özet

Prolaps gastropati gastrik mukozanın bir kısmının distal özofagus içine prolabe olması sonucu sınırları belirgin hemorajik mukoza ve bazen de kanama ile seyreden klinik sendromdur. Bu sendromun önemi hematemez nedeni olarak rapor edilmiş olmasıdır. Prolaps gastropatinin öğürme-kusma yakınmaları olan hastalarda görülmesi ve üst gastrointestinal sistem kanama nedeni olarak tanımlanması nedeniyle hastalarımızda bu sendromun sıklığını ve önemini araştırdık. Yöntem: Çalışmaya hematemez yakınması olan 941 hasta ile tekrarlayan öğürme-kusma yakınması olan 54 hasta alındı. Endoskopi sırasında prolaps gastropati tespit edilen vakalardan biyopsiler alındı. Preparatlar hematoksilen eosin ile boyanarak incelendi. Bulgular: Hematemez grubunda 6 (%0.6) hasta, öğürme-kusma yakınmaları olan grupta 14 (%25.9) hasta olmak üzere toplam 20 (%2) hastada prolaps gastropati saptandı. Lezyonlar 10 (%50) hastada büyük kurvatur yönünde, 7(%35) hastada küçük kurvatur yönünde, 3(%15) hastada ön duvar yönünde yerleşmişti. Hematemez grubundaki 6 hastada prolaps gastropatiyi primer kanama nedeni olarak düşünmedik, çünkü bu hastaların hepsinde kanamayı izah edecek başka patolojiler mevcuttu. Biyopsilerin histolojik incelenmesinde akut inflamasyon, kronik inflamasyon ve submukozal kanama bulguları mevcuttu. Sonuç: Bizim çalışmamızda prolaps gastropatinin hematemez nedeni olmadığı görülmektedir. Hematemez mevcut olan bir hastada prolaps gastropati görülse bile diğer kanama nedenleri araştırılmalıdır.

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Cite This Article

YÖRÜK, G., AKSÖZ, K., BUYRAÇ, Z., ÜNSAL, B., YILDIZ, C. (2003). Prolaps gastropati üst gastrointestinal sistem kanama nedeni midir?. Turkish Journal of Gastroenterology, Cilt: 14 - Sayı: 2, 106–110. https://ajindex.com/articles/410917

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