Journals / Turkish Journal of Gastroenterology / 2009 / Cilt: 20 - Sayı: 4

Pankreas kuyruğunda büyük fonksiyonel bir somatostatinoma: Atipik BT görünümleri

A large functional somatostatinoma in the pancreatic tail: Atypical CT appearances

Pages
291–294
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To the best of our knowledge, this is the first description of multiple-phase spiral computed tomography findings of a functional somatostatinoma in the pancreatic tail and the largest thus far on reported computed tomography, with some differences compared with the previous reports.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Somatostatinomas are extremely rare endocrine tumors, and those with diameters above 2 cm are reported to increase the risk of metastasis significantly.
📊
Key Findings & Data:A 46-year-old woman with a history of recurrent mild upper abdominal pain and diarrhea for 10 months was admitted to our hospital.
💡
Conclusion & Impact:To the best of our knowledge, this is the first description of multiple-phase spiral computed tomography findings of a functional somatostatinoma in the pancreatic tail and the largest thus far on reported computed tomography, with some differences compared with the previous reports.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tomografi · Spiral Bilgisayarlı · Kadın

Abstract

Somatostatinomas are extremely rare endocrine tumors, and those with diameters above 2 cm are reported to increase the risk of metastasis significantly. We report a case of a large functional somatostatinoma in the pancreatic tail without metastases. A 46-year-old woman with a history of recurrent mild upper abdominal pain and diarrhea for 10 months was admitted to our hospital. Multiple-phase spiral computed tomography revealed a 10 cm x 8 cm, ill-defined, elliptic mass in the body and tail of the pancreas. There was a slightly heterogeneous enhancement on hepatic arterial phase and isodensity to the pancreatic parenchyma with small dotted necrosis within the middle region of the mass on hepatic portal venous and parenchymal phase, with patent splenic vein, dilated collaterals at the splenic hilum and no dilated pancreatic duct, resembling a diffuse infiltration tumor. To the best of our knowledge, this is the first description of multiple-phase spiral computed tomography findings of a functional somatostatinoma in the pancreatic tail and the largest thus far on reported computed tomography, with some differences compared with the previous reports.

Özet

Somatostatinomalar çok nadir endokrin tümörlerdir ve 2cm'den büyük çapa sahip olanlarda metastaz riskinin belirgin olarak arttığı rapor edilmiştir. Burada, pankreas kuyruğunda büyük, fonksiyonel ancak metastaz yapmamış bir somatostatinoma vakasını sunuyoruz. Kırkaltı yaşında bir kadın hasta, 10 aydır tekrarlayan hafif üst karın ağrısı ve ishal şikayetiyle hastanemize başvurdu. Multi -faz spiral Bilgisayarlı Tomografi pankreasın gövde ve kuyruğunda 10 x 8 cm'lik sınırları belirsiz elips şeklinde bir kitle lezyonu gösterdi. Kitlenin, hepatik arteriyel fazda hafif heterojen kontrastlandığı, hepatik venöz ve parenkimal fazda ise ortasında küçük noktasal nekrozlarla, pankreas parenkimiyle isodens olduğu izlendi. Bunun yanında splenik venin açık, dalak hilusunda dilate kollateraller ve pankreatik kanalda dilatasyon olmaması diffüz infiltre bir tümör izlenimi vermekteydi. Bildiğimiz kadarıyla bu, pankreas kuyruğunda yerleşen, şimdiye kadar Bilgisayarlı Tomografi ile rapor edilenlerin en büyüğü olan fonksiyonel somatostatinomanın, ilk multi �faz spiral Bilgisayarlı Tomografi tanımlamasıdır ve geçmiş raporlarla karşılaştırıldığında bazı farklılıklar içermektedir.

🔖

Cite This Article

YU, R., CHEN, Y., WANG, L., XU, X., JIANG, D. (2009). Pankreas kuyruğunda büyük fonksiyonel bir somatostatinoma: Atipik BT görünümleri. Turkish Journal of Gastroenterology, Cilt: 20 - Sayı: 4, 291–294. https://ajindex.com/articles/410852

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (15)

  1. Nesi G, Marcucci T, Rubio CA, et al. Somatostatinoma: clinico- pathological features of three cases and literature reviewed. J Gastroenterol Hepatol 2007; [Epub ahead of print]
  2. Harris GJ, Tio F, Cruz AB Jr. Somatostatinoma: a case report and review of the literature. J Surg Oncol 1987; 36: 8-6
  3. Tjon A Tham RT, Jansen JB, Falke TH, et al. Imaging features of somatostatinoma: MR, CT, US, and angiography. J Comput Assist Tomogr 1994; 18: 427-31
  4. Buetow PC, Miller DL, Parrino TV, Buck JL. Islet cell tumors of the pancreas: clinical, radiologic, and pathologic correlation in diagnosis and localization. Radiographics 1997; 17: 453-72
  5. Larsson LI, Hirsch MA, Holst JJ, et al. Pancreatic somatostatinoma. Clinical features and physiological implications. Lancet 1977; 26: 666-8
  6. Soga J, Yakuwa Y. Somatostatinoma/inhibitory syndrome: a statistical evaluation of 173 reported cases as compared to other pancreatic endocrinomas. J Exp Clin Cancer Res 1999; 18: 13-22
  7. Debas HT, Mulvihill SJ. Neuroendocrine gut neoplasms. Important lessons from uncommon tumors. Arch Surg 1994; 129: 965-71
  8. Ganda OP, Weir GC, Soeldner JS, et al. "omatostatinoma" a somatostatin-containing tumor of the endocrine pancreas. N Engl J Med 1977; 296: 963-7
  9. Kaneko H, Yanaihara N, Ito S, et al. Somatostatinoma of the duodenum. Cancer 1979; 44: 2273-9
  10. Tomassetti P, Migliori M, Lalli S, et al. Epidemiology, clinical features and diagnosis of gastroenteropancreatic endocrine tumours. Ann Oncol 2001; 12 (Suppl): S95-9
  11. Usui M, Matsuda S, Suzuki H, et al. Somatostatinoma of the papilla of Vater with multiple gastrointestinal stromal tumors in a patient with von Recklinghausen's disease. J Gastroenterol 2002; 37: 947-53
  12. Jensen RT, Norton JA. Endocrine tumors of the pancreas. In: Sleisinger MH, Fordtran JS, eds. Gastrointestinal disease: pathophysiology/diagnosis/management. Philadelphia, PA: W.B. Saunders Co, 1993; 1695-721
  13. Soga J, Yakuwa Y. Somatostatinoma/inhibitory syndrome: a statistical evaluation of 173 reported cases as compared to other pancreatic endocrinomas. J Exp Clin Cancer Res 1999; 18: 13-22
  14. Mao C, Shah A, Hanson DJ, et al. Von Recklinghausen's disease associated with duodenal somatostatinoma: contrast of duodenal versus pancreatic somatostatinomas. J Surg Oncol 1995; 59: 67-73
  15. Tanaka S, Yamasaki S, Matsushita H, et al. Duodenal somatostatinoma: a case report and review of 31 cases with special reference to the relationship between tu