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Journals / Turkish Journal of Gastroenterology / 2017 / Cilt: 28 - Sayı: 2

Decreasing prevalence of Helicobacter pylori according to birth cohorts in urban China

Xinjuan YU
Xuan YANG
Tingting YANG
Quanjiang DONG
Lili WANG
Lei FENG
Pages
94–97
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: The overall H. pylori prevalence was found to be 31.9%, with the highest prevalence in the 1950-1959 birth cohort.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/Aims: The Helicobacter pylori (H. pylori) prevalence has been decreasing in many parts of the world.
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Key Findings & Data:This study aimed to investigate the current epidemiological status of H. pylori infection in urban China.Materials and Methods: The study included 51,299 subjects aged >=18 years who underwent health checkups between April 2013 and June 2016 in a city of China.
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Conclusion & Impact:Results: The overall H. pylori prevalence was found to be 31.9%, with the highest prevalence in the 1950-1959 birth cohort.
🔬Design:Modeling & Simulation
📍Scope:2013 Verileri
⚙️Variables:Domain Parameters

Özet

Background/Aims: The Helicobacter pylori (H. pylori) prevalence has been decreasing in many parts of the world. This study aimed to investigate the current epidemiological status of H. pylori infection in urban China.Materials and Methods: The study included 51,299 subjects aged >=18 years who underwent health checkups between April 2013 and June 2016 in a city of China. H. pylori infection was determined by detecting H. pylori urease-IgG antibodies. Statistical analyses included chi-square tests for trends and curve fitting. Results: The overall H. pylori prevalence was found to be 31.9%, with the highest prevalence in the 1950-1959 birth cohort. It was lower in the subsequent birth cohorts (trends, p<0.001). The decrease in H. pylori prevalence was correlated with the increase in per capita gross domestic product (GDP) and real per capita GDP; the power model was best fitted (R2=0.914 and 0.997 and p=0.011 and 0.000, respectively). Conclusion: There has been a striking decrease in the H. pylori prevalence in urban China. The birth cohort effect and economic growth are the most likely causes of this phenomenon.

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Cite This Article

YU, X., YANG, X., YANG, T., DONG, Q., WANG, L., FENG, L. (2017). Decreasing prevalence of Helicobacter pylori according to birth cohorts in urban China. Turkish Journal of Gastroenterology, Cilt: 28 - Sayı: 2, 94–97. https://ajindex.com/articles/410704

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References (4)

  1. Salama NR, Hartung ML, Muller A. Life in the human stomach: Per- sistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev Microbiol 2013; 11: 385-99. [CrossRef] Franceschi F, Gasbarrini A, Polyzos SA, Kountouras J. Extragastric dis- eases and Helicobacter pylori. Helicobacter 2015; 20(Suppl 1): 40-6. [CrossRef] Hunt RH, Xiao SD, Megraud F, et al. Helicobacter pylori in develop- ing countries. World gastroenterology organisation global guide- line. J Gastrointestin Liver Dis 2011; 20: 299-304.
  2. Malaty HM, El-Kasabany A, Graham DY, et al. Age at acquisition of Helicobacter pylori infection: A follow-up study from infancy to adulthood. Lancet 2002; 359: 931-5. [CrossRef] Weck MN, Brenner H. Apparent incidence of Helicobacter pylori in adulthood: To what extent do new infections reflect misclassifica- tion? Helicobacter 2011; 16: 266-75. [CrossRef] Banatvala N, Mayo K, Megraud F, Jennings R, Deeks JJ, Feldman RA. The cohort effect and Helicobacter pylori. J Infect Dis 1993; 168: 219-21. [CrossRef] den Hoed CM, Vila AJ, Holster IL, et al. Helicobacter pylori and the birth cohort effect: Evidence for stabilized colonization rates in childhood. Helicobacter 2011; 16: 405-9. [CrossRef] Goh KL, Chan WK, Shiota S, Yamaoka Y. Epidemiology of Helico- bacter pylori infection and public health implications. Helicobacter 2011; 16(Suppl 1): 1-9. [CrossRef] Pandeya N, Whiteman DC. Prevalence and determinants of Heli- cobacter pylori sero-positivity in the Australian adult community. J Gastroenterol Hepatol 2011; 26: 1283-9. [CrossRef] Xie C, Lu NH. Review: Clinical management of Helicobacter pylori infection in China. Helicobacter 2015; 20: 1-10. [CrossRef] Xia Y, Meng G, Zhang Q, et al. Dietary patterns are associated with Helicobacter pylori infection in Chinese adults: a cross-sectional study. Sci Rep 2016; 6: 32334. [CrossRef] Sathian B, Bhatt CR, Jayadevan S, Ninan J, Baboo NS, Sandeep G. Prediction of cancer cases for a hospital in Nepal: a statistical mod- elling. APJCP 2010; 11: 441-5.
  3. Chen HL, Chen MJ, Shih SC, Wang HY, Lin IT, Bair MJ. Prevalence of Helicobacter pylori infection and identification of risk factors in rural and urban Beijing, China. Helicobacter 2009; 14: 128-33. [CrossRef] Chen SY, Liu TS, Fan XM, et al. Epidemiological study of Helico- bacter pylori infection and its risk factors in Shanghai. Zhonghua Yi Xue Za Zhi 2005; 85: 802-6.
  4. Chen J, Bu XL, Wang QY, Hu PJ, Chen MH. Decreasing seroprevalence of helicobacter pylori infection