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Journals / Turkish Journal of Gastroenterology / 1999 / Cilt: 10 - Sayı: 3

The efficacy of 5-ASA preparations in prevention of postoperative recurrence of Crohn's disease (Retrospective assessment)

Crohn hastalığının postoperatif rekürrensinin önlenmesinde 5-ASA preparatlarının etkinliği (Retrospektif değerlendirme)

Erkan PARLAK
Aysel ÜLKER
Canan ALKIM
Bilge TUNÇ
Ahmet TEZEL
ÜLKÜ DAĞLI
Pages
276–279
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, postoperative drug treatment is effective in decreasing the risk of recurrence of Crohn's disease following surgical resection.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Recurrence of Crohn's disease frequently occurs after surgery.
📊
Key Findings & Data:The symptomatic recurrence rate (symptom plus endoscopic and/or radiological confirmation of disease) in the treatment group was 23.1% (3/13) compared with 50% (5/10) in the control group (p<0.05).
💡
Conclusion & Impact:In conclusion, postoperative drug treatment is effective in decreasing the risk of recurrence of Crohn's disease following surgical resection.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Crohn hastalığı · Cerrahi · Anti-enflamatuvar ajanlar

Abstract

Recurrence of Crohn's disease frequently occurs after surgery. A retrospective trial was performed to determine whether sulphasalazine or mesalamine are effective in decreasing the risk of recurrent Crohn's disease following surgical resection. The symptomatic recurrence rate (symptom plus endoscopic and/or radiological confirmation of disease) in the treatment group was 23.1% (3/13) compared with 50% (5/10) in the control group (p<0.05). In conclusion, postoperative drug treatment is effective in decreasing the risk of recurrence of Crohn's disease following surgical resection.

Özet

Cerrahi sonrası Crohn hastalığı rekürrensi sıklıkla ortaya çıkmaktadır. Sülfasalazin veya mesalaminin cerrahi rezeksiyon yapıldıktan sonra rekürren Crohn hastalığı riskini azaltmada etkili olup olmadığını anlamak için bir retrospektif çalışma yapıldı. Tedavi verilen grupta semptomatik rekürrens oranı (semptom ve endoskopik ve/veya radyolojik hastalık) %23.1 (3/13) iken, kontrol grubunda %50 (5/10) idi (p<0.05). Sonuçta, postoperatif ilaç tedavisinin cerrahi rezeksiyon yapıldıktan sonra Crohn Hastalığı'nın rekürrens riskini azaltmada etkili olduğu sonucuna varıldı.

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Cite This Article

PARLAK, E., ÜLKER, A., ALKIM, C., TUNÇ, B., TEZEL, A., DAĞLI, Ü. (1999). The efficacy of 5-ASA preparations in prevention of postoperative recurrence of Crohn's disease (Retrospective assessment). Turkish Journal of Gastroenterology, Cilt: 10 - Sayı: 3, 276–279. https://ajindex.com/articles/410552

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