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Journals / Turkish Journal of Gastroenterology / 1999 / Cilt: 10 - Sayı: 3

Brunner's gland mucus within the lamina propria of duodenal biopsies: A potential source of diagnostic error

Duodenum biyopsilerinde lamina propria içinde Brunner glandlara ait fibriler mukoid görünüm: Tanıda yanıltıcı görünüm

İnanç Elif GÜRER
Vildan TAŞKIN
Robert M. GENTA
Rodger C. HAGGIT
Pages
190–192
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We discuss the appearance of Brunner's glands in normal duodenal biopsies with particular reference to this potentially misleading artifact.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cellular and mucinous debris may accumulate in the lumen of Brunner' s glands and may be squeezed into the lamina propria of the duodenal villi by the trauma of a biopsy.
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Key Findings & Data:In this location, this fibrillary, PAS - positive material may mimic the appearance of a distinct structure that can be misinterpreted as a nerve bundle, a hamartoma, the macrophages of Whipple' s disease or other abnormalities.
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Conclusion & Impact:We discuss the appearance of Brunner's glands in normal duodenal biopsies with particular reference to this potentially misleading artifact.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Brunner bezleri · Tanı hataları · Biyopsi

Abstract

Cellular and mucinous debris may accumulate in the lumen of Brunner' s glands and may be squeezed into the lamina propria of the duodenal villi by the trauma of a biopsy. In this location, this fibrillary, PAS - positive material may mimic the appearance of a distinct structure that can be misinterpreted as a nerve bundle, a hamartoma, the macrophages of Whipple' s disease or other abnormalities. We discuss the appearance of Brunner's glands in normal duodenal biopsies with particular reference to this potentially misleading artifact.

Özet

Brunner gland lümenlerinde selüler ve müsinöz debri birikebilir ve biyopsi travmasına bağlı olarak , duodenal villuslerin lamina propriasında ezilebilir. Fibriler PAS pozitif materyal bu lokalizasyonda bazı yapıları taklit edebilir ve sinir lifleri, hamartomlar, Whipple hastalğındaki makrofajlar ya da diğer anomaliler olarak yanlış yorumlanabilir. Bu çaışmada normal duodenum biyopsilerinde bir artefakt olarak görülebilen Brunner bezlerinin potansiyel olarak yanlış tanılara neden olabileceğine dikkat çekilmektedir.

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Cite This Article

GÜRER, İ. E., TAŞKIN, V., GENTA, R. M., HAGGIT, R. C. (1999). Brunner's gland mucus within the lamina propria of duodenal biopsies: A potential source of diagnostic error. Turkish Journal of Gastroenterology, Cilt: 10 - Sayı: 3, 190–192. https://ajindex.com/articles/410546

References (7)

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