Journals / Turkish Journal of Gastroenterology / 2001 / Cilt: 12 - Sayı: 4

Hepatit C ve sarkoidozis birlikteliği: Olgu sunumu

The coexistence of sarcoidosis and hepatitis C: A case report

Pages
314–316
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The coexistence of both diseases in the same patient suggested that chronic hepatitis C infection might play a part in the occurrence of sarcoidosis via an undetermined immunopathogenic mechanism.

📌 3 Key Takeaways

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Objective & Hypothesis:Sarcoidosis is a multisystemic, chronic granulomatous disorder of unknown etiology.
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Key Findings & Data:Although a number of infectious and non-infectious causes have been suggested, no specific agent has been identified as yet.
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Conclusion & Impact:The coexistence of both diseases in the same patient suggested that chronic hepatitis C infection might play a part in the occurrence of sarcoidosis via an undetermined immunopathogenic mechanism.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hepatit C virüsleri · Hepatit C · Sarkoidoz

Abstract

Sarcoidosis is a multisystemic, chronic granulomatous disorder of unknown etiology. Although a number of infectious and non-infectious causes have been suggested, no specific agent has been identified as yet. Hepatitis C virus infection may result in chronic hepatitis and cirrhosis and extrahepatic manifestations of Hepatitis C virus include autoimmune and rheumatic diseases and a high prevalence of autoantibodies. The association of sarcoidosis with hepatitis C infection has been reported rarely. We report the case of an asymptomatic chronic Hepatitis C virus infection found in a young male patient following prednisolone treatment for pulmonary sarcoidosis. The coexistence of both diseases in the same patient suggested that chronic hepatitis C infection might play a part in the occurrence of sarcoidosis via an undetermined immunopathogenic mechanism.

Özet

Sarkoidozis etyolojisi bilinmeyen, multisistemik kronik granülamatöz bir hastalıktır. Biyolojide bir çok enfeksiyöz ve non-enfeksiyöz nedenler düşünülmüşse de, henüz spesifik bir ajan bu durumdan sorumlu tutulamamıştır. Hepatit C virüs enfeksiyonu kronik hepatit ve siroza neden olabilen bir hastalıktır. Hepatit C virüs enfeksiyonunun ekstrahepatik bulguları içinde otoimmün ve romatizmal hastalıklar sık görülmekte olup, yapılan bir çok çalışmada Hepatit C virüs enfeksiyonunda otoantikor yapımında artma tespit edilmiştir. Bir erkek hastada pulmoner sarkoidozis nedeniyle prednizolon tedavisinden sonra asemptomatik kronik Hepatit C virüs enfeksiyonu tespit edildi. Aynı hastada her iki hastalığın birlikte bulunması, kronik hepatit C enfeksiyonunun bilinmeyen immünopatojenik bir mekanizmayla sarkoidosiz oluşumunda rol oynayabileceğini düşündürmektedir.

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Cite This Article

ERDİL, A., TÜZÜN, A., KADAYIFÇI, A., UYGUN, A., YÜKSEKOL, İ., DEVECİ, M. S., DAĞALP, K. (2001). Hepatit C ve sarkoidozis birlikteliği: Olgu sunumu. Turkish Journal of Gastroenterology, Cilt: 12 - Sayı: 4, 314–316. https://ajindex.com/articles/410466

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