Journals / Turkish Journal of Gastroenterology / 2005 / Cilt: 16 - Sayı: 1

Kolorektal kanser gelişmiş familial adenomatöz polipozislerde restoratif proktokolektomi

Restorative proctocolectomy for familial adenomatous polyposis coexisting with colorectal cancer

Pages
44–47
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As an initial procedure, restorative proctocolectomy for patients with familial adenomatous polyposis with coexisting Stage I-II colorectal cancer seems to be a dependable procedure.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to assess whether restorative proctocolectomy was suitable as an initial procedure for selected familial adenomatous polyposis patients with coexisting colorectal cancer.
📊
Key Findings & Data:No evidence of tumor recurrence was found and all the patients are still alive and disease-free in follow-up (mean 28 months).
💡
Conclusion & Impact:As an initial procedure, restorative proctocolectomy for patients with familial adenomatous polyposis with coexisting Stage I-II colorectal cancer seems to be a dependable procedure.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Adenomatöz poliposis koli · Kolorektal neoplazmlar · Proktokolektomi

Abstract

The aim of this study was to assess whether restorative proctocolectomy was suitable as an initial procedure for selected familial adenomatous polyposis patients with coexisting colorectal cancer. Six malignancy patients who underwent restorative proctocolectomy for familial adenomatous polyposis were reviewed. At the time of restorative proctocolectomy, cancer was not suspected in four patients. The two remaining familial adenomatous polyposis patients had a known associated colorectal cancer. Operative procedures, pathological findings, complications and long-term follow-up were evaluated. All patients were Stage I-II cancers. There was no mortality or pouch failure. No evidence of tumor recurrence was found and all the patients are still alive and disease-free in follow-up (mean 28 months). As an initial procedure, restorative proctocolectomy for patients with familial adenomatous polyposis with coexisting Stage I-II colorectal cancer seems to be a dependable procedure.

Özet

Bu çalışmanın amacı, kolorektal kanser gelişmiş bazı hastalarda ilk seçenek olarak restoratif proktokolektominin yapılıp yapı lamayacağını araştırmaktır. Restoratif proktokolektomi yapı- lan familial adenomatöz polipozisli altı kolorektal kanser hastası retrospektif olarak incelendi. Restoratif proktokolektomi yapılırken dört hastada kanser teşhis edilememişti. Kalan iki hastada ise ameliyat öncesi kanser tanısı bilinmekteydi. Ameliyat bulguları, patolojik değerlendirmeler, komplikasyonlar ve uzun dönem takipler incelendi. Tüm hastalar Evre I-II kanserlerden oluşuyordu. Hiçbir hastada mortalite ve poş kaybı olmadı. Hiçbir hastada tumor nüksü gözlenmedi ve tüm hastalar halne hastalıksız olarak hayattadırlar (ortalama 28 ay). Evre III kolorektal kanserlerle birlikte olan familial adenomatöz polipozis hastalarında ilk seçenek olarak restoratif proktokolektomi uygulanması mantıklı görünmektedir

🔖

Cite This Article

KAYAALP, C., IŞIK, S., AKBABA, S., NEŞŞAR, G., OYMACI, E., SEVEN, C. (2005). Kolorektal kanser gelişmiş familial adenomatöz polipozislerde restoratif proktokolektomi. Turkish Journal of Gastroenterology, Cilt: 16 - Sayı: 1, 44–47. https://ajindex.com/articles/410380

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Jang YS, Steinhagen RM, Heimann TM. Colorectal cancer in familial adenomatous polyposis. Dis Colon Rectum 1997; 40: 312-6
  2. Madden MV, Neale KF, Nicholls RJ, et al. Comparison of morbidity and function after colectomy with ileorectal anastomosis or restorative proctocolectomy for familial adenomatous polyposis. Br J Surg 1991; 78: 789-92
  3. Nyam DC, Brillant PT, Dozois RR, et al. Ileal pouch-anal canal anastomosis for familial adenomatous polyposis: early and late results. Ann Surg 1997; 226: 514-9
  4. American Joint Committee on Cancer. Staging of Colorectal Cancer. In: Manual for Staging of Cancer (3rd ed.) Philadelphia: J.B. Lippincott; 1992. (2. revizion) pp: 87-95 5. Wiltz O, Hashmi HF, Schoetz DJ Jr, et al. Carcinoma and the ileal pouch-anal anastomosis. Dis Colon Rectum 1991; 34: 805-9
  5. Ziv Y, Church JM, Oakley JR, et al. Results after restorative proctocolectomy and ileal pouch-anal anastomosis in patients with familial adenomatous polyposis and coexisting colorectal cancer. Br J Surg 1996; 83: 1578-80
  6. Stenson WF, McDermott RP. Inflammatory bowel disease. In: Yamada T (ed.). Textbook of Gastroenterology. Philadelphia: J.B. Lippincott; 1991: 1588-645
  7. Setti-Carraro P, Nicholls RJ. Choice of prophylactic surgery for the large bowel component of familial adenomatous polyposis. Br J Surg 1996; 83: 885-92
  8. Kartheuser AH, Parc R, Penna CP, et al. Ileal pouch-anal anastomosis as the first choice operation in patients with familial adenomatous polyposis: a ten-year experience. Surgery 1996; 119: 615-23
  9. Taylor BA, Wolff BG, Dozois RR, et al. Ileal pouch-anal anastomosis for chronic ulcerative colitis and familial polyposis coli complicated by adenocarcinoma. Dis Colon Rectum 1996; 31: 358-62
  10. Stelzner M, Fonkalsrud EW. The endorectal ileal pullthrough procedure in patients with ulcerative colitis and familial polyposis with carcinoma. Surg Gynecol Obstet 1989; 169: 187-94.