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Journals / Turkish Journal of Gastroenterology / 2017 / Cilt: 28 - Sayı: 1

What is proton pump inhibitors unresponsiveness in gastroesophageal reflux disease? How should these cases be managed?

Altay ÇELEBİ
Hasan YILMAZ
Pages
71–72
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We reviewed the definition of PPI unresponsiveness and the management of this situation

📌 3 Key Takeaways

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Objective & Hypothesis:Proton pump inhibitors become the most potent therapeutic option in gastroesophageal reflux disease.
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Key Findings & Data:Unresponsiveness to this treatment is not uncommon in clinical practice.
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Conclusion & Impact:We reviewed the definition of PPI unresponsiveness and the management of this situation
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Proton pump inhibitors become the most potent therapeutic option in gastroesophageal reflux disease. Unresponsiveness to this treatment is not uncommon in clinical practice. We reviewed the definition of PPI unresponsiveness and the management of this situation

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Cite This Article

ÇELEBİ, A., YILMAZ, H. (2017). What is proton pump inhibitors unresponsiveness in gastroesophageal reflux disease? How should these cases be managed?. Turkish Journal of Gastroenterology, Cilt: 28 - Sayı: 1, 71–72. https://ajindex.com/articles/410204

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References (1)

  1. Fass R, Shapiro M, Dekel R, Sewel J. Systematic review: protonpump inhibitor failure in gastro-oesophageal reflux disease - where next? Aliment Pharmacol Ther 2005; 22: 79-94. [CrossRef] 2. Fass R, Sifrim D. Management of heartburn not responding to proton pump inhibitors. Gut 2009; 58: 295-309. [CrossRef] 3. Richter JE. The patient with refractory gastroesophageal reflux disease. Dis Esophagus 2006; 19: 443-7. [CrossRef] 4. Dellon ES, Shaheen HJ. Persistent reflux symptoms in the proton pump inhibitor era: The changing face of gastroesophageal reflux disease. Gastroenterology 2010; 139: 7-13. [CrossRef] 5. Kohata Y, Fujiwara Y, Machida H, et al. Pathogenesis of proton pump inbitor refractory non-erosive reflux disease according to multichannel intraluminal impedance-pH monitoring. J Gastroenterol Hepatol 2012; 27(Suppl3):58-62. [CrossRef] 6. Ribolsi M, Emerenziani S, Borrelli O, et al. Impedance baseline and reflux perception in responder and non-responder non-erosive reflux disease patients. Scan J Gastroenterol 2012; 47: 1266-73. [CrossRef] 7. Sifrim D, Zerbib F. Diagnosis and management of patients with reflux symptoms refractory to proton pump inhibitors. Gut 2012; 61: 1340-54. [CrossRef] 8. Hershcovici T, Fass R. Management of gastroesophagealrefluxdiseasethatdoes not respondwellto proton pumpinhibitors. Curr Opin Gastroenterol 2010; 26: 367-78. [CrossRef] 9. Hershcovici T, Fass R. Step by step management refractory gastroesophageal reflux disease. Dis Esophagus 2013; 26: 27-36. [CrossRef] 10. Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol 2013; 108: 308-28. [CrossRef]