Journals / Turkish Journal of Gastroenterology / 2007 / Cilt: 18 - Sayı: 2

Kemik iliği tutulumu ve osteoblastik kemik metastazları olan rektal karsinoid tümör: Olgu sunumu

Rectal carcinoid tumor with bone marrow and osteoblastic bone metastasis: A case report

Pages
111–114
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Bone marrow involvement might be a poor prognostic factor in carcinoid tumor as has been the case in many other tumors.

📌 3 Key Takeaways

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Objective & Hypothesis:Rectal carcinoids comprise 12.6% of all carcinoid tumors and represent the third largest group of the gut carcinoids.
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Key Findings & Data:A 64-year- old woman was diagnosed as high-grade neuroendocrine carcinoma.
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Conclusion & Impact:Bone marrow involvement might be a poor prognostic factor in carcinoid tumor as has been the case in many other tumors.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kadın · Ölümle sonuçlanma · Orta yaşlı

Abstract

Rectal carcinoids comprise 12.6% of all carcinoid tumors and represent the third largest group of the gut carcinoids. A 64-year- old woman was diagnosed as high-grade neuroendocrine carcinoma. She had liver, bone, and bone marrow metastasis. Carcinoid syndrome was diagnosed due to diarrhea, nausea, vomiting, tachycardia, and high level of 24-hour urinary 5- hydroxyindoleacetic acid (160 mg/24 hours). No response was obtained by octreotide treatment. Rectal carcinoid tumors usually show favorable prognosis; however, poorly differentiated tumors might have unusually aggressive behavior and resistance to treatment. Bone marrow involvement might be a poor prognostic factor in carcinoid tumor as has been the case in many other tumors.

Özet

Rektal karsinoidler tüm karsinoidlerin %12,6’sını ve barsak karsinoidlerinin üçüncü en büyük grubunu oluşturmaktadır. Altmış dört yaşında kadın hastaya yüksek greydli nöroendokrin karsinom tanısı konuldu. Hastada karaciğer, kemik ve kemik iliği metastazı vardı. Diyare, bulantı-kusma, taşikardi ve yüksek 24 saatlik 5-H‹AA (160 mg/24 saat) olması nedeniyle karsinoid sendrom tanısı aldı. Rektal karsinoid tümörler genellikle iyi prognoza sahip olmakla birlikte kötü diferansiye olanları agreziv davranış ve tedaviye direnç gösterebilirler. Kemik iliği tutulumu diğer tümörlerde olduğu gibi karsinoid tümörlerde de kötü prognostik faktör olabilir.

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Cite This Article

ÖZKAN, M., ER, Ö., KARAHAN, Ö., DENİZ, K., COŞKUN, R., KÜÇÜK, C., YURCİ, A., ALTINBAŞ, M. (2007). Kemik iliği tutulumu ve osteoblastik kemik metastazları olan rektal karsinoid tümör: Olgu sunumu. Turkish Journal of Gastroenterology, Cilt: 18 - Sayı: 2, 111–114. https://ajindex.com/articles/409948

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