İran’da B ve C Hepatiti Ko-enfeksiyonu: Serolojik - epidemiyolojik bir çalışma

Conclusion: The seroprevalence of co-infection with hepatitis B virus and hepatitis C virus in our study was higher than such reports from some countries (Italy), but was in line with worldwide prevalence (>10%).

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: As hepatitis B and C virus have the same transmission routes, dual infection may occur.

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Key Findings & Data:Methods: 139 HBsAg-positive subjects were enrolled in the study.

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Conclusion & Impact:Conclusion: The seroprevalence of co-infection with hepatitis B virus and hepatitis C virus in our study was higher than such reports from some countries (Italy), but was in line with worldwide prevalence (>10%).

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Seroepidemiyolojik çalışmalar · Enzim bağlı immünosorbent tayini · Hepatit C

Abstract

Background/aims: As hepatitis B and C virus have the same transmission routes, dual infection may occur. The aim of this study was to determine the seroprevalence of HCV in HBsAg-positive subjects. Methods: 139 HBsAg-positive subjects were enrolled in the study. Serum samples were tested using ELISA method for anti-HCV antibodies. Chi-square and Fisher's exact tests were used to compare the proportions. Results: There were 68 (48.9%) males and 71 (51.1%) females. The mean age was 41.89±11.30 years. One case was excluded because of inadequate blood sampling. Anti-HCV antibody was positive in 17 (12.3%) of the 138 remaining subjects. Seropositivity of HCV was similar between female and male patients (p=0.69). Conclusion: The seroprevalence of co-infection with hepatitis B virus and hepatitis C virus in our study was higher than such reports from some countries (Italy), but was in line with worldwide prevalence (>10%).

Özet

Amaç: B ve C hepatitlerinin bulaş yolları aynı olduğu için ikili enfeksiyonlar ortaya çıkabilmektedir. Bu araştırmanın amacı, HBsAg pozitif hastalarda HCV seropozitişiğinin araştırılması dır. Yöntem: 139 HBsAg pozitif hasta çalışmaya alındı. Bu hastaların serum örnekleri anti-HCV pozitifliği açısından ELISA yöntemi ile incelendi. Oranların karşılaştırılması için Chi-kare ve Fisher’ın doğrulama testleri kullanıldı. Bulgular: 68 (%48,9) erkek ve 71 (%51,1) kadın hasta mevcuttu. Ortalama yaş 41,89±11,30 yıldı. Bir hasta yetersiz miktarda alınan kan örneği nedeniyle çalışma dışı bırakıldı. Geriye kalan 138 hastalanı n 17’sinde (%12,3) anti-HCV pozitişiği tespit edildi. Kadı n ve erkek hastalardaki seropozitişik sıklığı benzer bulundu. (p= 0,69) Sonuç: B ve C hepatitlerin birlikte enfekte hasta prevalansı benzer prevalans sonuçları veren ülkelerinkinden (İtalya) yüksektir ancak dünya genelindeki prevalansa (>%10) benzerdir.

Keywords

Seroepidemiyolojik çalışmalar Enzim bağlı immünosorbent tayini Hepatit C Örnekleme çalışmaları Antikorlar viral Hepatit B virüsü İran Hepacivirus Seroepidemiologic Studies Enzyme-Linked Immunosorbent Assay Hepatitis C Sampling Studies Antibodies Viral Hepatitis B virus Iran

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Cite This Article

SEMNANI, S., ROSHANDEL, G., ABDOLAHI, N., BESHARAT, S., KESHTKAR, A., JOSHAGHANI, H., MORADI, A., KALAVI, K., JABBARI, A., KABIR, M. J., HOSSEINI, S. A., SEDAQAT, S. M., DANESH, A., ROSHANDEL, D. (2007). İran’da B ve C Hepatiti Ko-enfeksiyonu: Serolojik - epidemiyolojik bir çalışma. Turkish Journal of Gastroenterology, Cilt: 18 - Sayı: 1, 20–21. https://ajindex.com/articles/409947

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