Journals / Turkish Journal of Gastroenterology / 2010 / Cilt: 21 - Sayı: 2

Anadoluda anne ve bebeklerinde Helikobakter pilori enfeksiyonu

Helicobacter pylori infection in mother and infant pairs in Anatolia

Pages
113–118
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is possible that the decrease in breastfeeding with in- creased introduction of supplemental foods may lead to an in- creased risk of exposure to Helicobacter pylori.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this prospective study was to determine the seroprevalence rates of Helicobacter pylori in mother and infant pairs and to discuss the possible fecal-oral transmission route of Helicobacter pylori infection in the early years of life.
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Key Findings & Data:Methods: Forty-eight mother-child pairs were fol- lowed for 12 months.
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Conclusion & Impact:It is possible that the decrease in breastfeeding with in- creased introduction of supplemental foods may lead to an in- creased risk of exposure to Helicobacter pylori.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this prospective study was to determine the seroprevalence rates of Helicobacter pylori in mother and infant pairs and to discuss the possible fecal-oral transmission route of Helicobacter pylori infection in the early years of life. Methods: Forty-eight mother-child pairs were fol- lowed for 12 months. Helicobacter pylori IgG and hepatitis A vi- rus (HAV) IgG levels were measured in maternal sera, infant se- ra and breast-milk samples at birth and in breast-milk samp- les and infant sera at follow-up visits. Results: At birth, the ra- te of Helicobacter pylori positivity was 81.25% in breast-milk and 95.8% in maternal and infant sera. Although there was a decrease in seropositivity in both baby sera and breast-milk at the age of nine months, an increase was observed in the 12th month. Hepatitis A virus IgG was measured to show whether Helicobacter pylori and hepatitis A virus use the same trans- mission routes. Hepatitis A was positive in all infants' sera, in 95.8% of mothers' sera, and in 68.75% of breast-milk samples. Seropositivity rates in infants whose mothers were seropositive for Helicobacter pylori and hepatitis A virus decreased gradu- ally. There was an increase after the 9th month of life. Conclu- sions: Helicobacter pylori seroprevalence rates are high in Ana- tolia. It is possible that the decrease in breastfeeding with in- creased introduction of supplemental foods may lead to an in- creased risk of exposure to Helicobacter pylori.

Özet

Bu prospektif çalışmanın amacı anne ve bebek örneklerinde Helikobakter pilori seroprevelansını belirlemek ve hayatın erken dönemlerinde olası fekal-oral geçiş yolunun tartışılmasıdır. Yöntem: Bu prospektif çalışmada 48 anne-bebek çifti oniki ay süre ile izlendi. Doğumda alınan anne kanı, bebek kanı ve anne sütü örnekleri ile aylık izlemlerde alınan anne sütü ve bebek kanında Helikobakter pilori IgG ve Hepatit A IgG değerleri ölçüldü. Sonuçlar: Doğumda anne sütündeki Helikobakter pilori IgG pozitişiği %81.25, anne ve bebek serumda %95.8 idi. 9. aya kadar bebeklerin serumunda ve anne sütünde Helikobakter pilori seroprevelansında azalma olmasına karşın 12. ayda hem bebek serumu hemde anne sütü Helikobakter pilori seroprevelansında artış oldu. Helikobakter pilori enfeksiyonun geçiş yolunun değerlendirilmesi için Hepatit A IgG bakıldı ve tüm bebek serumlarında, anne serumlarının %95.8'inde ve anne sütünün %68.75'inde pozitif saptandı. Annelerinde Helikobakter pilori IgG pozitişiği olan bebeklerin serumlarındaki antikor pozitişiği bebeğin yaşı ilerledikçe azalma gösterdi, ancak 9. aydan sonra yeniden artış gözlendi. Tartışma: Anadolu'da Helikobakter pilori seroprevelansı yüksektir. Anne sütü alımının azalması ile ek gıdalara geçiş döneminde Helikobakter pilori enfeksiyonu ile karşılaşma riskini artıyor olabilir.

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Cite This Article

HIZEL, S., ÖZDEN, A., TANZER, F., KISA, Ü., MISIRLIOĞLI, D. E., BÜYÜKKAYHAN, D., KISA, Ö. (2010). Anadoluda anne ve bebeklerinde Helikobakter pilori enfeksiyonu. Turkish Journal of Gastroenterology, Cilt: 21 - Sayı: 2, 113–118. https://ajindex.com/articles/409776

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