Journals / Turkish Journal of Gastroenterology / 2011 / Cilt: 22 - Sayı: 5

Akut biliyer pankreatitli hastalarda ana safra kanalı taşları varlığı hastalığın şiddetini ve laboratuvar bulgularını etkiler mi?

Does presence of common bile duct stones in patients with acute biliary pancreatitis affect the severity of illness or laboratory findings?

Pages
517–522
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Presence of common bile duct stones do not correlate with the severity of acute biliary pancreatitis.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: To determine the effect of stone within the common bile duct, on the severity of acute biliary pancreatitis.
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Key Findings & Data:Material and Methods: This is a prospective and cross sectional study which was conducted at a tertiary care hospital including 103 patients.
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Conclusion & Impact:Conclusion: Presence of common bile duct stones do not correlate with the severity of acute biliary pancreatitis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aims: To determine the effect of stone within the common bile duct, on the severity of acute biliary pancreatitis. Material and Methods: This is a prospective and cross sectional study which was conducted at a tertiary care hospital including 103 patients. Serum biochemical values and white blood cell counts at the first 12th and 72nd hours of presentation were evaluated. The patients were grouped according to the presence or absence of common bile duct stones which were diagnosed by endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography. Besides, the patients were classified as mild and severe acute pancreatitis according to the data provided by computed tomography (Balthazar scoring) and clinical assessment and blood samples. Results: Among the 103 patients with acute biliary patients, radial endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography revealed stones and/or sludge within the common bile duct or ampulla in 41 (39.8%) patients. There was not any persistent common bile duct stone in 62 (60.2%) patients. Severe pancreatitis developed in 9 (22%) of 41 patients who were determined to have stones by endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography, and in 13 (21%) of 62 patients who were not. There was no difference in the incidence of progressing to severe acute biliary patients between patients with and without common bile duct stones (p=0.45). Conclusion: Presence of common bile duct stones do not correlate with the severity of acute biliary pancreatitis.

Özet

Amaç: Akut biliyer pankreatitin şiddeti ile ilgili olarak ana safra kanalındaki taşların etkisini tanımlamak. Yöntem: Bu tersiyer bir hastanede 103 hastalık, prospektif ve cross sectional olarak yapılmış bir çalışmadır. Başvurunun ilk 12 ve 72. saatlerindeki serum biyokimyasal ve beyaz küre sayımları değerlendirildi. Hastalar, endoskopik ultrasonografi ve endoskopik retrograd kolanjiopankreatografide tanımlanan ana safra kanalı taşlarının varlığına göre gruplandırıldı. Bunun yanında hastalar bilgisayarlı tomografi ve kan örneklerinden derlenen verilerle (Baltazar skorlamasına göre) hafif ve ciddi akut pankreatit olarak sınıflandı. Bulgular: Akut biliyer pankreatitli 103 hasta arasında, 41 (%39,8) hastada endoskopik ultrasonografi ve endoskopik retrograd kolanjiopankreatografi ile ana safra kanalı veya ampullada taş ve/veya çamur saptandı. Altmışiki (%60,2) hastada ana safra kanalında taş yoktu. Endoskopik ultrasonografi ve endoskopik retrograd kolanjiopankreatografide taş saptanan 41 hastanın 9'unda (%22), saptanmayan 62 hastanın 13'ünde (%21) şiddetli pankreatit gelişti. Ana safra kanalında taş olan ve olmayan hastalar arasında şiddetli akut biliyer pankreatite gidiş insidansında fark saptanmadı (p=0.45). Sonuç: Ana safra kanalı taşları varlığı akut biliyer pankreatit şiddeti ile ilişkili değildir.

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Cite This Article

ALPER, E., BAYDAR, B., VATANSEVER, S., BUYRAÇ, Z., ASLAN, F., AKPINAR, Z., AKSÖZ, M. K., AKÇA, S., ÜNSAL, B. (2011). Akut biliyer pankreatitli hastalarda ana safra kanalı taşları varlığı hastalığın şiddetini ve laboratuvar bulgularını etkiler mi?. Turkish Journal of Gastroenterology, Cilt: 22 - Sayı: 5, 517–522. https://ajindex.com/articles/409728

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