SavedAdd your journal

Journals / Turkish Journal of Gastroenterology / 2011 / Cilt: 22 - Sayı: 6

Displastik nevus sendromunda primer safra kesesi melanomu: Olgu sunumu ve literatür taraması

Primary gallbladder melanoma in dysplastic nevus syndrome: Report of case and literature review

Jasmina GLIGORIJEVIC
Vesna ZIVKOVIC
Biljana DJORDJEVIC
Irena DIMOV
Pages
626–630
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This is only the second case reported to date of primary malignant melanoma in dysplastic nevus syndrome.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A case of gallbladder malignant melanoma in a 62-year-old woman is reported.
📊
Key Findings & Data:These cells with pigment were positive immunohistochemically for S-100, HMB45 and vimentin.
💡
Conclusion & Impact:This is only the second case reported to date of primary malignant melanoma in dysplastic nevus syndrome.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A case of gallbladder malignant melanoma in a 62-year-old woman is reported. The gallbladder, resected for tumor mass seen on ultrasound examination, revealed neoplastic epithelioid cells with dark granules in the cytoplasm. These cells with pigment were positive immunohistochemically for S-100, HMB45 and vimentin. The patient, affected by dysplastic nevus syndrome, had a history of a melanoma in situ in her left upper arm that was excised 11 years ago. This is only the second case reported to date of primary malignant melanoma in dysplastic nevus syndrome.

Özet

Burada safra kesesi malign melanomu olan 62 yaşındaki kadın hasta sunulmuştur. Ultrason tetkikinde saptanan tümöral kitle nedeniyle rezeke edilen safra kesesinde, sitoplazmik koyu granüller içeren epiteloid hücreler saptandı. Bu pigmentli hücreler, immünohistokimyasal olarak S-100, HMB45 ve vimentin için pozitif idi. Hastanın displastik nevus sendromu vardı ve 11 yıl önce sol kolundan in situ melanom eksizyonu öyküsü bulunuyordu. Bu olgu, displastik nevus sendromunda şimdiye dek bildirilmiş ikinci primer malign melanom olgusudur.

🔖

Cite This Article

GLIGORIJEVIC, J., ZIVKOVIC, V., DJORDJEVIC, B., DIMOV, I. (2011). Displastik nevus sendromunda primer safra kesesi melanomu: Olgu sunumu ve literatür taraması. Turkish Journal of Gastroenterology, Cilt: 22 - Sayı: 6, 626–630. https://ajindex.com/articles/409718

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (21)

  1. Higgins CM, Strutton GM. Malignant melanoma of the gallbladder-does primary melanoma exist? Pathology 1995; 27: 312-4
  2. Safioleas M, Agapitos E, Kontzoglou K, et al. Primary melanoma of gallbladder: Does it exist? Report of case and review of literature. World J Gastroenterol 2006; 12(26): 4259-61
  3. Wieting H, Hamdi G. Uber die phisiologyshe und pathologische Melaninpigmentierung und den epithelialen. Ursprung der melanoblastome.Ein primares melanoblastom der gallenblase. Beitr Anat Allg Pathol 1907; 42: 24-84
  4. Rosenthal SR. Primary melanocarcinoma of the gallbladder. Am J Cancer 1931; 15: 2289-300
  5. Pautler EE, Gallavan EM. Primary melanocarcinoma of the gallbladder. Arch Pathol 1951; 51: 238-45
  6. Thayer KH, Williams OO, Rowe D. Malignant melanoma of the gallbladder. Ariz Med 1955; 12: 15-8
  7. Walsh TS. Primary melanoma of gallbladder with cervical metastases and fourteen and a half years survival. Cancer 1956; 6: 518-22
  8. Jones CH. Malignant melanoma of the gallbladder. J Pathol Bact 1961; 81: 423-30
  9. Raffensperger EC, Branson FW, Triano G. Primary melanoma of the gallbladder. Am J Dig Dis 1963; 8: 356-363
  10. Debiec H, Kirylowicz K, Hrba Z. Dwa przypadki czarniaka zlosliwogo pecherzka zolciowego. Przegl Lek 1966; 6: 643-5
  11. Simmard C, George P, Cautlet T, et al. Les mélanomes maligns de la vésicule biliare. Raport de deux cas. J Chir (Paris) 1966; 92: 51-8
  12. Peison B, Rabin L. Malignant melanoma of the gall bladder: report of three cases and review of the literature. Cancer 1976; 37: 2448-54
  13. Sierra-Callejas JL, Warecka K. Primary malignant melanoma of the gallbladder. Virchows Arch 1976; 370: 233-8
  14. Hatae Y, Kikuchi M, Segawa M, et al. Malignant melanoma of gallbladder. Pathol Res Practice 1978; 163: 281-7
  15. Carle G, Lessels AM, Best PV. Malignant melanoma of the gallbladder: a case report. Cancer 1981; 48: 2318-22
  16. Anderson JB, Hughes RG, Williamson RN. Malignant melanoma of the gallbladder. Postgrad Med 1983; 59: 390-1
  17. Borja RS, Meyer WR, Cahill JP. Malignant melanoma of gallbladder: report of a case. Cancer 1984; 54: 929-31
  18. Naguib SE, Aterman K. Presumed primary malignant melanoma of the gallbladder: report of a case and a review of literature. Am J Dermatopathol 1984; 6 (Suppl 1): 231-43
  19. Seul B, Luchtrath H. Malignes melanomes der gallenblase. Chirurg 1984; 55: 179-81
  20. Rudolph A, Bothe J, Bonk U. Malignes melanom der gallenblase. Chirurg 1985; 56: 469-71
  21. Verbanck JJ, Rutgeerts LJ, Va