Journals / Turkish Journal of Gastroenterology / 2011 / Cilt: 22 - Sayı: 6

‹mmunosüpresif ilaç alan ülseratif kolitli hastalarda Kaposi sarkomu: Olgu sunumu

Kaposi’s sarcoma in patients with ulcerative colitis receiving immunosuppressive drugs: Report of a case

Pages
621–625
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cases of colorectal Kaposi’s sarcoma complicating inflammatory bowel disease should be managed with a conservative approach and discontinuation of the immunosuppressive treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Kaposi’s sarcoma is an unusual tumor principally affecting the skin of the lower extremities.
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Key Findings & Data:Although the association between Kaposi’s sarcoma and renal transplant has been well documented, there are few Kaposi’s sarcoma cases in the literature associated with ulcerative colitis or other inflammatory bowel diseases.
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Conclusion & Impact:Cases of colorectal Kaposi’s sarcoma complicating inflammatory bowel disease should be managed with a conservative approach and discontinuation of the immunosuppressive treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Kaposi’s sarcoma is an unusual tumor principally affecting the skin of the lower extremities. Although the association between Kaposi’s sarcoma and renal transplant has been well documented, there are few Kaposi’s sarcoma cases in the literature associated with ulcerative colitis or other inflammatory bowel diseases. This report presents a patient with ulcerative colitis who developed Kaposi’s sarcoma following treatment with long-term medium-dose azathioprine and additional corticosteroids. Kaposi’s sarcoma is a rare complication in inflammatory bowel diseases that may (or may not) be related to immunosuppression. Hence, immunomodulatory agents should be planned carefully in the treatment of inflammatory bowel diseases and avoided if they are not essentially necessary. Cases of colorectal Kaposi’s sarcoma complicating inflammatory bowel disease should be managed with a conservative approach and discontinuation of the immunosuppressive treatment.

Özet

Kaposi sarkomu genellikle alt ekstremiteleri etkileyen nadir rastlanılan bir tümördür. Kaposi sarkomu ile renal transplantasyon arasındaki ilişki iyi bilinmesine rağmen literatürde ülseratif kolit veya diğer inflamatuvar bağırsak hastalıklarıyla ilişkili az sayı da olgu bildirilmiştir. Biz ülseratif kolit nedeniyle azathioprine ve ek olarak kortikosteroid tedavisini takiben Kaposi sarkomu gelişen bir vakayı takdim ettik. Kaposi sarkomu immunosüpresyonla ilişkili olarak veya olmayarak inflamatuvar bağırsak hastalı- ğının nadir bir komplikasyonudur. Bundan dolayı immunomodülator ajanlar inflamatuvar bağırsak hastalığının tedavisinde dikkatli planlanmalı ve gerekli olmadıkça kaçınılmalıdır. inflamatuvar bağırsak hastalığının komplikasyonu olarak ortaya çıkan Kaposi sarkomlu vakalar konservatif yaklaşımlarla yönetilmeli ve immünosupresif tedaviye devam edilmemelidir.

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Cite This Article

ÇETİN, B., BÜYÜKBERBER, S., YILMAZ, I. B., YILDIZ, R., COŞKUN, U., BENEKLİ, M. (2011). ‹mmunosüpresif ilaç alan ülseratif kolitli hastalarda Kaposi sarkomu: Olgu sunumu. Turkish Journal of Gastroenterology, Cilt: 22 - Sayı: 6, 621–625. https://ajindex.com/articles/409717

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