Journals / Turkish Journal of Gastroenterology / 2012 / Cilt: 23 - Sayı: 5

Antakya yöresinde yüksek anti-HCV seroprevalansı ve risk faktörleri

Risk factors for higher anti-HCV positivity in a border city in southern Turkey with unique population characteristics

Pages
574–579
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: The overall anti-hepatitis C virus prevalence was 3.1% (44/1427).

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aims: This study was conducted as a seroprevalence study on hepatitis C virus infection in a small city located in southern Anatolia, to estimate the prevalence of hepatitis C virus and to explore the potential risk factors for hepatitis C virus infection at this population level.
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Key Findings & Data:Material and Methods: A total of 1427 (685 male (48%), 742 female) subjects agreed to participate in the study.
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Conclusion & Impact:Results: The overall anti-hepatitis C virus prevalence was 3.1% (44/1427).
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background/aims: This study was conducted as a seroprevalence study on hepatitis C virus infection in a small city located in southern Anatolia, to estimate the prevalence of hepatitis C virus and to explore the potential risk factors for hepatitis C virus infection at this population level. Material and Methods: A total of 1427 (685 male (48%), 742 female) subjects agreed to participate in the study. Risk factors were examined using a questionnaire. All blood samples were tested using third-generation anti-hepatitis C virus enzyme-linked immunosorbent assays. Results: The overall anti-hepatitis C virus prevalence was 3.1% (44/1427). There was a steady rise in the prevalence of anti-hepatitis C virus positivity with age; the anti-hepatitis C virus prevalence was slightly higher in men (3.6%) than women (2.6%). The prevalence of anti-hepatitis C virus positivity was significantly higher in primary school graduates (3.4%) (odds ratio [OR]: 4.1, 95% confidence interval [CI]: 1.5-11.6, p=0.0001) and in illiterate subjects (5.0%) (OR: 2.7, 95% CI: 1.1-7.4, p=0.021) compared to secondary-plus graduates. Anti-hepatitis C virus positivity was higher (3.7%) in married subjects (OR: 8.7, 95% CI: 1.2-63.7, p=0.003) compared to single subjects (0.0%). Having dental procedure, delivery at home, provocative abortion, working abroad, hypertension, and diabetes mellitus were factors found to increase the anti-hepatitis C virus positivity significantly. Conclusions: In the region of the current study, the anti-hepatitis C virus seroprevalence was higher compared to the whole country. Illiteracy, previous dental procedures, and working abroad in neighboring countries seem to be factors that relate to this high ratio.

Özet

Amaç: Bu çalışma güney Anadolunun bir sınır şehrinde anti-hepatit C virus seroprevalansını saptamak, ikincil olarak da bu popülasyondaki potansiyel risk faktörlerini belirlemek amacıyla yapılmıştır. Gereç ve Yöntem: Çalışmaya 685 erkek, 742 kadın toplam 1427 birey alındı. Risk faktörleri bir anket formu ile sorgulandı. Tüm kan örnekleri anti-hepatit C virus için 3. jenerasyon enzyme- linked immunosorbent assays yöntemi ile analiz edildi. Bulgular: Toplam anti-hepatit C virus prevalansı 3.1% (44/1427) saptandı. Erkeklerde anti-hepatit C virus pozitişiği (3.6%) kadınlara göre daha fazla (2.6%) idi ve prevalans yaşla birlikte artmaktaydı. Anti-hepatit C virus prevalansı ilkokul mezunları (3.4%) (OR: 4.1, 95% CI: 1.5-11.6, p= 0.0001) ve eğitimsizlerde (5.0%) (OR:2.7, 95% CI: 1.1-7.4, p=0.021) ortaokul ve üstü eğitimlilere göre anlamlı ölçüde daha yüksekti. Anti-hepatit C virus pozitişiği evlilerde (3.7%) bekarlara (0.0%) göre daha fazla idi (OR:8.7, 95% CI: 1.2-63.7, p=0.003). Diş müdahalesi, evde doğum, provakatif düşük, yurt dışında çalışma, hipertansiyon, diabetes mellitus öyküsüne sahip olmak artmış anti-hepatit C virus pozitişiği için anlamlı bulundu. Sonuç: Çalışmanın yapıldığı bölgede anti-hepatit C virus seroprevalansı ülke geneli ile karşılaştırıldığında daha yüksekti. Eğitimsiz, öncesinde diş müdahalesi ve komşu ülkelerde çalışmış olmak bu yüksek oranda etkili faktörler olarak gözükmektedir.

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Cite This Article

ÖZER, B., SEYDAOĞLU, G., ÖZŞAHİN, A. K., DEMİRHİNDİ, H. (2012). Antakya yöresinde yüksek anti-HCV seroprevalansı ve risk faktörleri. Turkish Journal of Gastroenterology, Cilt: 23 - Sayı: 5, 574–579. https://ajindex.com/articles/409696

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