Journals / Turkish Journal of Gastroenterology / 2012 / Cilt: 23 - Sayı: 3

Farklı yaştaki kaynağı bilinmeyen gastrointestinal sistem kanamalarının en sık görülen nedenlerinin kapsül endoskopi ile tespit edebilirliği

Capsule endoscopy examination identifies different leading causes of obscure gastrointestinal bleeding in patients of different ages

Pages
220–225
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Overall, the detection rates for positive capsule endoscopy findings in the elderly, middle-aged and young adult groups were 66.94%, 62.29% and 61.80%, respectively, and the diagnostic rates were 48.76%, 45.14% and 53.93%, respectively.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aims: We aimed to investigate the diagnostic applications of capsule endoscopy examination patients in obscure gastrointestinal bleeding and to analyze the etiology of obscure gastrointestinal bleeding in patients of different ages.
📊
Key Findings & Data:Material and Methods: A total of 385 patients with obscure gastrointestinal bleeding, aged 17–91 years, were assigned into three groups as: elderly (>65 years), middle-aged (41-65 years) and young adults (17-40 years).
💡
Conclusion & Impact:Results: Overall, the detection rates for positive capsule endoscopy findings in the elderly, middle-aged and young adult groups were 66.94%, 62.29% and 61.80%, respectively, and the diagnostic rates were 48.76%, 45.14% and 53.93%, respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Gastrointestinal kanama · Kapsül endoskopi · Yaş dağılımı

Abstract

Background/aims: We aimed to investigate the diagnostic applications of capsule endoscopy examination patients in obscure gastrointestinal bleeding and to analyze the etiology of obscure gastrointestinal bleeding in patients of different ages. Material and Methods: A total of 385 patients with obscure gastrointestinal bleeding, aged 17–91 years, were assigned into three groups as: elderly (>65 years), middle-aged (41-65 years) and young adults (17-40 years). Gastrointestinal examinations were carried out in each participant with the use of a capsule endoscopy diagnostic system. Results: Overall, the detection rates for positive capsule endoscopy findings in the elderly, middle-aged and young adult groups were 66.94%, 62.29% and 61.80%, respectively, and the diagnostic rates were 48.76%, 45.14% and 53.93%, respectively. No significant difference existed in either rate between the different age groups. The commonest pathological changes detected were vascular malformations, intestinal tumors, Crohn's disease, non-specific enteritis, and small intestine ulcer, but the distribution of these causes for obscure gastrointestinal bleeding varied between the different age groups. The top three common reasons for obscure gastrointestinal bleeding in the elderly group were vascular malformations, small intestine ulcers and small intestine tumors, while in the middle-aged group vascular malformation, small intestine tumor and non-specific enteritis were the most common. The young adults were most likely to have Crohn's disease, small intestine tumors or non-specific enteritis. Conclusions: Capsule endoscopy examination not only shows potential diagnostic value for obscure gastrointestinal bleeding, but it also helps to identify the leading causes of obscure gastrointestinal bleeding in all age groups.

Özet

Amaç: Nedeni bilinmeyen gastrointestinal kanamaların odaklarının tespit edilmesi ve kapsül endoskopinin bu kanamalardaki tanı sal etkinliğinin incelenmesi amaçlanmıştır. Yöntem ve Gereç: Nedeni bilinmeyen gastrointestinal kanaması olan, 17-91 yaş arası toplam 385 hasta yaşlı (>65), orta yaşlı (41-65 yıl) ve genç erişkinler (17-40 yıl) olmak üzere 3 gruba ayrıldı. Her bir hasta kapsül endoskopi kullanılarak incelendi. Bulgular: Yaş gruplarına göre pozitif kapsül endoskopi bulunma oranları yaşlı, orta yaşlı ve genç erişkin gruplarında sırasıyla %66,94, %62,29 ve %61,80 olarak ve doğru tanısal oranları sırasıyla %48,76, %45,14 ve %53,93 olarak bulundu. Her iki oran açısından yaş grupları arasında anlamlı bir farklılık bulunmadı. En sık tespit edilen patolojiler, vasküler malformasyonlar, intestinal tümörler, Crohn hastalığı, non-spesifik enterit ve ince barsak ülserleri olarak bulundu, ancak bu patolojilerin yaş gruplarına göre dağılımı anlamlı olarak farklılıklar göstermekteydi. Yaşlı grupta en sık karşılaşı- lan nedeni bilinmeyen gastrointestinal kanama nedenleri vasküler malformasyonlar, ince barsak ülserleri ve ince barsak tümörleri olarak bulundu. Orta yaşlı grupta vasküler malformasyonlar, ince barsak tümörleri ve non-spesifik enterit olarak bulundu. Genç erişkin grubunda ise Crohn hastalığı, ince barsak tümörleri ve non-spesifik enterit olarak tespit edildi. Sonuç: Kapsül endoskopi incelemesi nedeni bilinmeyen gastrointestinal kanamalarda tanı koyma potansiyeline sahiptir ve tüm yaş gruplarında en sık karşı laşılan kanama nedenlerini ortaya koyabilmektedir.

🔖

Cite This Article

ZHANG, B., CHEN, C., LI, Y. (2012). Farklı yaştaki kaynağı bilinmeyen gastrointestinal sistem kanamalarının en sık görülen nedenlerinin kapsül endoskopi ile tespit edebilirliği. Turkish Journal of Gastroenterology, Cilt: 23 - Sayı: 3, 220–225. https://ajindex.com/articles/409674

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Fireman Z, Friedman S. Diagnostic yield of capsule endoscopy in obscure gastrointestinal bleeding. Digestion 2004; 70: 201-6
  2. Adler DG, Knipschield M, Gostout C. A prospective comparison of capsule endoscopy and push enteroscopy in patients with GI bleeding of obscure origin. Gastrointest Endosc 2004; 59: 492-8
  3. Mylonaki M, Fritscher-Ravens A, Swain P. Wireless capsule endoscopy: a comparison with push enteroscopy in patients with gastroscopy and colonoscopy negative gastrointestinal bleeding. Gut 2003; 52: 1122-6
  4. Bresci G, Parisi G, Bertoni M, et al. The role of video capsule endoscopy for evaluating obscure gastrointestinal bleeding: usefulness of early use. J Gastroenterol 2005; 40: 256-9
  5. Garcia-Compean D, Armenta JA, Gonzalez JA, et al. Diagnostic utility and clinical impact of capsule endoscopy in obscure gastrointestinal bleeding. Preliminary results. Rev Gastroenterol Mex 2005; 70: 120-8
  6. Hadithi M, Heine GD, Jacobs MA, et al. A prospective study comparing video capsule endoscopy with double-balloon enteroscopy in patients with obscure gastrointestinal bleeding. Am J Gastroenterol 2006; 101: 52-7
  7. Jones BH, Fleischer DE, Sharma VK, et al. Yield of repeat wireless video capsule endoscopy in patients with obscure gastrointestinal bleeding. Am J Gastroenterol 2005; 100: 1058-64
  8. Mata A, Bordas JM, Feu F, et al. Wireless capsule endoscopy in patients with obscure gastrointestinal bleeding: a comparative study with push enteroscopy. Aliment Pharmacol Ther 2004; 20: 189-94
  9. Triester SL, Leighton JA, Leontiadis GI, et al. A metaanalysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding. Am J Gastroenterol 2005; 100: 2407-18
  10. Zhang BL, Fang YH, Chen CX, et al. Single-center experience of 309 consecutive patients with obscure gastrointestinal bleeding. World J Gastroenterol 2009; 15: 5740-5
  11. Zhang BL, Jiang LL, Chen CX, et al. Diagnosis of obscure gastrointestinal hemorrhage with capsule endoscopy in combination with multiple-detector computed tomography. J Gastroenterol Hepatol 2010; 25: 75-9
  12. Appleyard M, Fireman Z, Glukhovsky A, et al. A randomized trial comparing wireless capsule endoscopy with push enteroscopy for the detection of small-bowel lesions. Gastroenterology 2000; 119: 1431-8
  13. Garofalo TE, Abdu RA. Accuracy and efficacy of nuclear scintigraphy for the detection of gastrointestinal bleeding. Arch Surg 1997; 132: 196-9