AI Summary & Key Takeaways
AI InsightWe suggest that for patients with gastric cancer who complain of the findings of acute cholecystitis or cholecystolithiasis, gallbladder metastasis from gastric cancer should be considered in the differential diagnosis.
📌 3 Key Takeaways
Abstract
Metastasis to the gallbladder from other malignancies is extremely rare and is related with a very poor prognosis. Malignant melanoma has been reported to be the most common origin of gallbladder metastasis. Although only eight cases of gallbladder metastasis originating from gastric cancer have been documented in the literature based on small series, of these cases, only one case with signet ring cell carcinoma histology has been reported previously. We report the case of a 58-year-old male with early-stage signet ring cell carcinoma of the stomach who presented with acute cholecystitis previously treated with curative gastrectomy. After laparoscopic cholecystectomy, the diagnosis of gallbladder metastasis with signet ring cell histology secondary to gastric cancer was made. To our knowledge, this is only the second case of signet ring cell carcinoma of the stomach metastasized to the gallbladder as a first site of recurrence. We suggest that for patients with gastric cancer who complain of the findings of acute cholecystitis or cholecystolithiasis, gallbladder metastasis from gastric cancer should be considered in the differential diagnosis.
Özet
Malignitelere bağlı safra kesesine metastaz oldukça nadir olup, kötü prognozla ilişkilidir. Malign melanom safra kesesi metastazı nın ek sık köken aldığı kanser olarak bildirilmiştir. Mide kanserine bağlı safra kesesi metastazı küçük bir seriye dayanarak yalnızca 8 olgu olarak dokümente edilmiş olmasına rağmen, bu vakalardan yalnızca bir tanesi taşlı yüzük hücreli karsinom histolojisi ile bildirilmiştir. Bu yazıda 58 yaşında küratif gastrektomi uygulanmış ve akut kolesistitle prezente olan erken evre taşlı yüzük hücreli mide kanserli vaka sunuldu. Laparoskopik kolesistektomi sonrasında mide kanserine bağlı taşlı yüzük hücreli safra kesesi metastazı tanısı konuldu. Bilgimize göre, bu olgu ilk nüks bölgesi olarak taşlı yüzük hücreli mide kanserine bağlı ikinci safra kesesi metastazı olgusudur. Akut kolesistit ya da kolanjit bulgularıyla başvuran mide kanserli hastalarda safra kesesi metastazı ayırcı tanıda akılda tutulmalıdır.