Journals / Turkish Journal of Gastroenterology / 2014 / Cilt: 25 - Sayı: 5

An easy method for diagnosing macro-aspartate aminotransferase: A case series

Pages
568–570
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This method is practical for primary healthcare facilities because of its easy application and accurate results, and obviated the need for unnecessary tests after diagnosis.

📌 3 Key Takeaways

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Objective & Hypothesis:Macro-aspartate transaminase (macro-AST) must be considered when the aspartate transaminase (AST) level is chronically high without any liver, cardiac, or muscle disease.
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Key Findings & Data:Our method is based on the decrease in the plasma AST level after storage of the macroenzyme at 2-8°C for 5 days, and has the advantages of low cost, reliability, and practicality at any health center.
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Conclusion & Impact:This method is practical for primary healthcare facilities because of its easy application and accurate results, and obviated the need for unnecessary tests after diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Macro-aspartate transaminase (macro-AST) must be considered when the aspartate transaminase (AST) level is chronically high without any liver, cardiac, or muscle disease. Many specialized laboratory techniques have been recommended for diagnosing macro-AST, including the polyethylene glycol immune precipitate technique, which is simple. This study presents a considerably easier method based on the studies of Davidson and Watson and Castiella et al. Our method is based on the decrease in the plasma AST level after storage of the macroenzyme at 2-8°C for 5 days, and has the advantages of low cost, reliability, and practicality at any health center. In our eight cases of macro-AST, the AST activity at day 6 had decreased by more than 50% from day 1. This method is practical for primary healthcare facilities because of its easy application and accurate results, and obviated the need for unnecessary tests after diagnosis.

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Cite This Article

BEŞER, Ö. F., LAÇİNEL, S., GÜLCÜ, D., KUTLU, T., ÇULLU, F. Ç., ERKAN, T. (2014). An easy method for diagnosing macro-aspartate aminotransferase: A case series. Turkish Journal of Gastroenterology, Cilt: 25 - Sayı: 5, 568–570. https://ajindex.com/articles/409548

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References (7)

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