Journals / Turkish Journal of Gastroenterology / 2019 / Cilt: 30 - Sayı: 9

Efficacy and safety of endoscopic retrograde cholangiopancreatography in pregnancy: A high-volume study with long-term follow-up

Pages
811–816
DOI
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⚡ TL;DR(Too Long; Didn't Read)

After the deliveries, the newborns were apparently healthy during the follow-up period of 1–7 years.Conclusion: Either conventional or non-radiation ERCP procedures can be performed successfully in pregnancy, with no increase in thenumber of feto-maternal complications when performed by experienced endoscopists.

📌 3 Key Takeaways

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Objective & Hypothesis:Background/Aims: Pancreaticobiliary diseases are observed more frequently in pregnancy due to increased biliary stone formation.There are some concerns about the use of endoscopic retrograde cholangiopancreatography (ERCP) because of potential fetal exposureto radiation and serious adverse events, such as post-ERCP pancreatitis, which increases fetal or maternal morbidity and mortality.
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Key Findings & Data:Theaim of this study was to evaluate the efficacy and safety of ERCP during pregnancy and to present our experience.Materials and Methods: This study included 25 pregnant patients who underwent ERCP due to biliopancreatic pathologies between2010 and 2017.
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Conclusion & Impact:After the deliveries, the newborns were apparently healthy during the follow-up period of 1–7 years.Conclusion: Either conventional or non-radiation ERCP procedures can be performed successfully in pregnancy, with no increase in thenumber of feto-maternal complications when performed by experienced endoscopists.
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:Domain Parameters

Özet

Background/Aims: Pancreaticobiliary diseases are observed more frequently in pregnancy due to increased biliary stone formation.There are some concerns about the use of endoscopic retrograde cholangiopancreatography (ERCP) because of potential fetal exposureto radiation and serious adverse events, such as post-ERCP pancreatitis, which increases fetal or maternal morbidity and mortality. Theaim of this study was to evaluate the efficacy and safety of ERCP during pregnancy and to present our experience.Materials and Methods: This study included 25 pregnant patients who underwent ERCP due to biliopancreatic pathologies between2010 and 2017. Indications for ERCP were choledocholithiasis (n=12), biliary pancreatitis (n=9), and acute cholangitis (n=4). ERCP procedures were performed using fluoroscopy (n=18) and the non-radiation technique (n=7). The duration of fluoroscopy was recorded in allcases. Fetal and maternal complications were both assessed.Results: The mean age of patients was 29.4 (range, 21–40) years, and the mean duration of pregnancy was 19.9 weeks. All the 25 ERCPprocedures were performed successfully. Biliary sphincterotomy was performed in all patients, and 18 patients with choledocholithiasisunderwent stone extraction. The average procedure duration was 11 min, and the average duration of fluoroscopy was 6 s. There were nomajor complications in any patient. After the deliveries, the newborns were apparently healthy during the follow-up period of 1–7 years.Conclusion: Either conventional or non-radiation ERCP procedures can be performed successfully in pregnancy, with no increase in thenumber of feto-maternal complications when performed by experienced endoscopists.

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Cite This Article

KONDUK, B. T., BAYRAKTAR, O. (2019). Efficacy and safety of endoscopic retrograde cholangiopancreatography in pregnancy: A high-volume study with long-term follow-up. Turkish Journal of Gastroenterology, Cilt: 30 - Sayı: 9, 811–816. https://ajindex.com/articles/409293

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References (16)

  1. Everson GT, McKinley C, Kern Jr F. Mechanisms of gallstone formation in women: effects of exogenous estrogen (Premarin) and dietary cholesterol on hepatic lipid metabolism. J Clin Invest 1991
  2. [CrossRef] 2. Marzio L. Factors affecting gallbladder motility: drugs. Dig Liver Dis 2003
  3. [CrossRef] 3. Maringhini A, Ciambra M, Baccelliere P, et al. Biliary sludge and gallstones in pregnancy: incidence, risk factors, and natural history. Ann Intern Med 1993
  4. [CrossRef] 4. Valdivieso V, Covarrubias C, Siegel F, et al. Pregnancy and cholelithiasis: pathogenesis and natural course of gallstones diagnosed in the early puerperium. Hepatology 1993
  5. [CrossRef] 5. Glenn FS, McSherry CK, Charles K. Gallstones and pregnancy among 200 young women treated with cholecystectomy. Surg Gynecol Obstet 1968
  6. Valdivesio V, Covarrubias C, Siegel F, et al. Pregnancy and cholelithiasis: Pathogenesis and natural course of gallstones diagnosed in early puerperium. Hepatology 1993
  7. [CrossRef] 7. Di Leo M, Arcidiacono PG. Fetal radiation exposure: Is monitoring really needed? World J Gastrointest Endosc 2013
  8. [CrossRef] 8. Shelton J, Linder JD, Rivera-Alsina ME, et al. Commitment, confirmation, and clearance: new techniques for nonradiation ERCP during pregnancy (with videos). Gastrointest Endosc 2008
  9. [CrossRef] 9. McGrath BA, Singh M, Singh T, et al. Spontaneous common bile duct rupture in pregnancy. Int J Obstet Anesth 2005
  10. [CrossRef] 10. Al-Hashem H, Muralidharan V, Cohen H, Jamidar PA. Biliary disease in pregnancy with an emphasis on the role of ERCP. J Clin Gastroenterol 2009
  11. [CrossRef] 11. Kahaleh M, Hartwell GD, Arseneau KO, et al. Safety and efficacy of ERCP in pregnancy. Gastrointest Endosc 2004
  12. [CrossRef] 12. International Commission on Radiological Protection. Pregnancy and medical radiation. Ann ICRP 2000
  13. iii-viii, 1-43. 13. Jamidar PA, Beck GJ, Hoffman BJ, et al. Endoscopic retrograde cholangiopancreatography in pregnancy. Am J Gastroenterol 1995
  14. Cotton PB, Lehman G, Vennes J, et al. Endoscopic sphincterotomy complications and their management: an attempt at consensus. Gastrointest Endosc 1991
  15. [CrossRef] 15. Tham TC, Vandervoort J, Wong RC, et al. Safety of ERCP during pregnancy. Am J Gastroenterol 2003
  16. [CrossRef] 16. Wilkinson EJ. Acute pancreatitis in pregnancy: a review of 98 cases and a report