AI Summary & Key Takeaways
AI InsightNo side effects werenoted.Conclusion: Both Celox and Surgicel are effective for controlling bleeding and are safe after a tooth extraction in patients with cirrhosis.
📌 3 Key Takeaways
Özet
Background/Aims: The management of patients with cirrhosis requiring dental extractions is complicated due to an increased risk ofpost-operative bleeding. Topical hemostatic agents are usually required to control bleeding in these cases, as an adjunct to systemicmeasures of hemostasis. The aims of this randomized, prospective, single-blind clinical study are twofold. The primary aim is to comparethe hemostatic efficacy of chitosan and surgicel in patients with cirrhosis after a tooth extraction, and the secondary aim is to assessthe value of the current setting as a clinical model of post-operative bleeding following minor oral surgery.Material and Methods: Fifty patients with cirrhosis scheduled for a tooth extraction under local anesthesia were prospectively includedin the study in a randomized fashion. Patients were blinded to the treatment group they were in. The cirrhosis classification, bleedingtime, trauma score, and corrected bleeding time (during post-operative reviews) were recorded. Statistical evaluations were done.Results: Study groups had an equal number of teeth extractions (40 teeth each). There were no statistically significant differences between the groups with respect to patient demographics, cirrhosis classification, trauma score, and bleeding time. No side effects werenoted.Conclusion: Both Celox and Surgicel are effective for controlling bleeding and are safe after a tooth extraction in patients with cirrhosis.