AI Summary & Key Takeaways
AI InsightA total of eight patients (5.7%) developedlocal recurrence, of which five were of nodular type and statistically significant (p=0.000).Conclusion: The most common type of ulcer healing was scar type after ESD, but nodular type was associated with local recurrence.When we perform follow-up endoscopy after ESD, we should pay attention to the lesion that has nodular change of mucosal surface.
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Özet
Background/Aims: To date, there are few reports on the clinical association between healing pattern of lesion and local recurrence afterendoscopic resection (ER). We examined the risk factors associated with local recurrence after endoscopic submucosal dissection (ESD)and the correlation between healing type of lesion and recurrence.Materials and Methods: We retrospectively analyzed medical records of 293 patients who underwent ESD of early gastric cancer orgastric adenoma between April 2010 and January 2012. We analyzed the relationship among factors such as age, location of lesion, size,pathologic diagnosis, presence of Helicobacter pylori (H. pylori), and healing types of ulcers in patients with local recurrence throughfollow-up endoscopic surveillance (1, 6, and 12 months after ESD).Results: We analyzed 141 patients except for patients who had not undergone surveillance endoscopy, H. pylori test, and ambiguoushealing patterns. There were no significant correlations between local recurrences concerning sex, age, tumor size, location, and pathologic diagnosis. When the healing type of the ulcer was divided into hypertrophic polypoid type (9 cases (6.4%)), scar type (122 cases(86.5%)), and nodular type (10 cases (7.1%)), the scar type was found to be most common. A total of eight patients (5.7%) developedlocal recurrence, of which five were of nodular type and statistically significant (p=0.000).Conclusion: The most common type of ulcer healing was scar type after ESD, but nodular type was associated with local recurrence.When we perform follow-up endoscopy after ESD, we should pay attention to the lesion that has nodular change of mucosal surface.